Health-Related Quality of Life of People Living with COPD in a Semiurban Area of Western Nepal: A Community-Based Study

Ballav Adhikari, TaraAarhus Univ, Dept Publ Hlth, Ctr Global Hlth, Aarhus, Denmark; Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal (author)

Health-Related Quality of Life of People Living with COPD in a Semiurban Area of Western Nepal : A Community-Based Study

Chronic Obstructive Pulmonary Disease (COPD) is a major cause of morbidity and mortality in Nepal. It is a progressive lung disease and has a significant impact on the quality of life of patients. Health-related quality of life (HRQOL) reflects the health- and disease-related facets of quality of life. Limited studies have assessed the impact of COPD on HRQOL and associated factors in Nepal. This study is based on a cross-sectional household survey data from a semiurban area of Western Nepal. A validated Nepali version of St George's Respiratory Questionnaire (SGRQ) was used to measure the HRQOL. COPD was defined together with post-bronchodilator airflow obstruction and the presence of respiratory symptoms. Post-bronchodilator airflow obstruction was defined as Forced Expiratory Volume in 1st second (FEV1) to Forced Vital Capacity (FVC) ratio < 0.70. COPD was diagnosed in 122 participants, and their median (IQR) total score of HRQOL was 40 (26 - 69); the score of symptoms, activity, and impact area were 53 (37 - 74), 57 (36 - 86), and 26 (13 - 62), respectively. The overall HRQOL was significantly different in terms of age, occupational status, physical activity, and comorbidities. Disease severity and the presence of respiratory symptoms had a significant difference in HRQOL (p = 0.0001). Appropriate measures to improve conditions and addressing the associated factors like respiratory symptoms and enhancing physical activity are necessary and important.

Rijal, AnupaNepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal; Univ Southern Denmark, Fac Hlth Sci, Dept Reg Hlth Res, Odense, Denmark (author)
Acharya, PawanNepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal; Univ Oklahoma, Hlth Sci Ctr, Hudson Coll Publ Hlth, Oklahoma City, OK USA (author)
Högman, MarieannUppsala universitet,Lung- allergi- och sömnforskning(Swepub:uu)marihogm (author)
Karki, ArjunHAMS Hosp, Dept Pulm Crit Care & Sleep Med, Kathmandu, Nepal (author)
Drews, ArneNepalmed, Leipzig, Germany (author)
Cooper, Brendan G.Univ Hosp Birmingham, Lung Funct & Sleep, Birmingham, W Midlands, England (author)
Sigsgaard, TorbenAarhus Univ, Dept Publ Hlth, Sect Environm Occupat & Hlth, Aarhus, Denmark (author)
Neupane, DineshNepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal; Johns Hopkins Univ, Dept Epidemiol, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA (author)
Kallestrup, PerAarhus Univ, Dept Publ Hlth, Ctr Global Hlth, Aarhus, Denmark (author)
Aarhus Univ, Dept Publ Hlth, Ctr Global Hlth, Aarhus, Denmark; Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, NepalNepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal; Univ Southern Denmark, Fac Hlth Sci, Dept Reg Hlth Res, Odense, Denmark (creator_code:org_t)

By the author/editor: Ballav Adhikari, ...; Rijal, Anupa; Acharya, Pawan; Högman, Marieann; Karki, Arjun; Drews, Arne; show more...; Cooper, Brendan ...; Sigsgaard, Torbe ...; Neupane, Dinesh; Kallestrup, Per; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Respiratory Medi ...

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