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Localized IgG4-rela...
Localized IgG4-related disease manifested on the tongue : a case report
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- Hashemi, Helya (author)
- Uppsala universitet,Käkkirurgi
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- Thor, Andreas (author)
- Uppsala universitet,Käkkirurgi
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- Hellbacher, Erik (author)
- Uppsala universitet,Reumatologi
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- Carlson, Marie, 1957- (author)
- Uppsala universitet,Gastroenterologi/hepatologi
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- Gulyas, Miklos, MD, PhD, Associate Professor (author)
- Uppsala universitet,Klinisk och experimentell patologi
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- Blomstrand, Lena (author)
- Uppsala universitet,Käkkirurgi
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(creator_code:org_t)
- 2021-05-11
- 2021
- English.
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In: Upsala Journal of Medical Sciences. - : Upsala Medical Society. - 0300-9734 .- 2000-1967. ; 126:1
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Abstract
Subject headings
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- Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that can affect multiple organs. IgG4-RD may show a variety of initial symptoms. In the oral mucosa, lesions present as inflammatory fibrosis with a large number of IgG4-positive plasma cells. Evaluating treatment is a well-known problem in IgG4-RD due to the absence of an established assessment system. There are difficulties in defining the severity of the disease, which is why treatment is primarily based on its clinical manifestations. We present a case report of localized IgG4-RD with ulcerative and proliferative manifestations on the tongue, which clinically mimicked oral squamous cell carcinoma. A tumor-like lesion on the tongue can indicate something else other than the malignant or reactive changes commonly found in the oral mucosa. Multiple differential diagnoses of these atypical oral lesions, including localized IgG4-RD, should be considered.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Keyword
- IgG4-related disease
- localized
- oral lesion
- tongue
- differential diagnosis
- histopathology
- monoclonal antibody
- Rituximab
- Pathology
- Patologi
Publication and Content Type
- ref (subject category)
- art (subject category)
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