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Morphological changes in mycobacteria

Ramesh, Malavika (author)
Uppsala universitet,Molekylärbiologi
Kirsebom, Leif A. (thesis advisor)
Løbner-Olesen, Anders, Professor (opponent)
Department of Biology, University of Copenhagen
 (creator_code:org_t)
ISBN 9789151313443
Uppsala : Acta Universitatis Upsaliensis, 2021
English 77 s.
Series: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology, 1651-6214 ; 2094
  • Doctoral thesis (other academic/artistic)
Abstract Subject headings
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  • Morphological variations at different stages and conditions of growth has been observed frequently in various mycobacteria. Despite years of research, the molecular basis of such variations is still not clear and requires further elucidation. Owing to the pathogenic significance of mycobacteria, currently, mycobacterial research emphasizes on understanding responses to oxygen deprivation, starvation, various antibiotic treatments, latency and dormancy.In this thesis, change in cell shape from rod to coccoid, occurrence of refractive spore-like phase grey, phase bright bodies and branching are some of the morphological variations discussed. Further, this thesis also discusses microaerobic condition (oxygen deprivation) and the localisation pattern of the stressosome complex. 

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Cell- och molekylärbiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Cell and Molecular Biology (hsv//eng)

Keyword

Mycobacteria
pleomorphism
dnaK_3
microaerobic condition
Morphology
oxygen deprivation
spore-like cells
Biology with specialization in Molecular Biology
Biologi med inriktning mot molekylärbiologi

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