Search: onr:"swepub:oai:DiVA.org:uu-462875" >
Targeting the Dieta...
Targeting the Dietary Na : K Ratio-Considerations for Design of an Intervention Study to Impact Blood Pressure.
- Article/chapterEnglish2021
Publisher, publication year, extent ...
-
Oxford University Press,2021
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:uu-462875
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-462875URI
-
https://doi.org/10.1093/advances/nmab099DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Despite medical, dietary, and lifestyle recommendations and drug advancements, hypertension persists as among the most prevalent noncommunicable diseases in the US population, and control remains elusive. Uncontrolled hypertension may increase the risk of serious illness from various other health challenges, including cardiovascular and renal responses. Adoption of a healthy diet is a consistent core element of lifestyle modifications that are recommended for mitigation of hypertension. The dietary sodium-to-potassium ratio is recognized as having promising potential in the regulation of blood pressure. In fact, the understanding of the relation between this ratio and blood pressure was documented as a key evidence gap in the 2019 National Academies of Sciences, Engineering, and Medicine report that revised recommended intake levels for both sodium and potassium. Although notable animal and human evidence supports this point, fundamental to developing a specific dietary recommendation for a sodium-to-potassium ratio is a well-designed human intervention trial. The successful translatability of such a trial will require careful consideration of study elements, including the study population, duration, blood pressure measurement, and dietary intervention, among other factors. This paper addresses these decision points and serves as supporting documentation for a research group or organization with the interest and means to address this important data gap, which will undoubtedly be foundational for advancing dietary guidance and would inform the next iteration of Dietary Reference Intakes for sodium and potassium.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Althouse, Andrew
(author)
-
Hermann, Mindy
(author)
-
Johnson, Janice
(author)
-
Maki, Kevin C
(author)
-
Marklund, MattiUppsala universitet,Klinisk nutrition och metabolism(Swepub:uu)matma701
(author)
-
Vogt, Liffert
(author)
-
Wesson, Donald
(author)
-
Stallings, Virginia A
(author)
-
Uppsala universitetKlinisk nutrition och metabolism
(creator_code:org_t)
Related titles
-
In:Advances in nutrition (Bethesda, Md.): Oxford University Press13:1, s. 225-2332156-53762161-8313
Internet link
Find in a library
To the university's database