Health-related quality of life in long-term survivors of childhood brain tumors: a population-based cohort study

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:DiVA.org:uu-485161" > Health-related qual...

1 of 1
Previous record
Next record
To hitlist

Health-related quality of life in long-term survivors of childhood brain tumors : a population-based cohort study

Ljungman, Lisa, 1981- (author): Uppsala universitet,Reproduktiv hälsa

Remes, Tiina (author): Univ Oulu, Oulu Univ Hosp, PEDEGO Res Unit, Dept Pediat & Adolescence, Oulu, Finland.;Univ Oulu, Oulu Univ Hosp, Med Res Ctr, Oulu, Finland.;Univ Helsinki, Helsinki Univ Hosp, Childrens Hosp, Dept Child Neurol, Helsinki, Finland

Westin, Elisabeth (author): Uppsala universitet,Institutionen för kvinnors och barns hälsa

Huittinen, Alina (author): Uppsala universitet,Institutionen för kvinnors och barns hälsa

Lonnqvist, Tuula (author): Univ Helsinki, Helsinki Univ Hosp, Childrens Hosp, Dept Child Neurol, Helsinki, Finland

Sirkia, Kirsti (author): Univ Helsinki, Helsinki Univ Hosp, Dept Pediat & Adolescence, Helsinki, Finland

Rantala, Heikki (author): Univ Oulu, Oulu Univ Hosp, PEDEGO Res Unit, Dept Pediat & Adolescence, Oulu, Finland.;Univ Oulu, Oulu Univ Hosp, Med Res Ctr, Oulu, Finland

Ojaniemi, Marja (author): Univ Oulu, Oulu Univ Hosp, PEDEGO Res Unit, Dept Pediat & Adolescence, Oulu, Finland.;Univ Oulu, Oulu Univ Hosp, Med Res Ctr, Oulu, Finland

Harila, Marika (author): Oulu Univ Hosp, Dept Neurol, Oulu, Finland

Lahteenmaki, Paivi (author): Turku Univ, Turku Univ Hosp, Dept Pediat & Adolescent Med, Turku, Finland

Arikoski, Pekka (author): Univ Eastern Finland, Kuopio Univ Hosp, Pediat Res Unit, Kuopio, Finland

Wikman, Anna (author): Uppsala universitet,Reproduktiv hälsa

Harila-Saari, Arja H. (author): Uppsala universitet,Institutionen för kvinnors och barns hälsa

show less...

(creator_code:org_t)

2022-03-03
2022
English.
In: Supportive Care in Cancer. - : Springer Nature. - 0941-4355 .- 1433-7339. ; 30:6, s. 5157-5166

Related links:: https://doi.org/10.1...; show more...; https://uu.diva-port... (primary) (Raw object); https://link.springe...; https://urn.kb.se/re...; https://doi.org/10.1...; show less...

Journal article (peer-reviewed)

Abstract Subject headings

Purpose Survivors of childhood brain tumors (BT) are at high risk for long-term physical and psychological sequelae. Still, knowledge about health-related quality of life (HRQL) and associated factors in this population is sparse. This study investigated HRQL and its predictors in long-term survivors of childhood BT.Methods Survivors of childhood BT (mean age = 28.1 years, SD = 6.8, n = 60) underwent clinical examination and neurocognitive examination, and completed self-rating questionnaires assessing HRQL (RAND-36) and depressive symptoms (Beck Depression Inventory-II). Socio-demographic information was gathered via a questionnaire. Tumor- and treatment-related information was collected from medical records. Control group data were collected from age-matched controls (n = 146) without a history of cancer, randomly selected from the local population registry. Multiple linear regression models were used to investigate predictors of HRQL; separate models were fitted for each domain of the RAND-36.Results Male survivors (mean age = 27.0, SD = 6.0, n = 39) reported significantly lower HRQL than male controls in the domains of physical functioning, general health, vitality, social functioning, and role limitations-emotional. Female survivors (mean age = 30.2 years, SD = 7.6, n = 21) reported comparable levels as female controls in all domains except physical functioning. A higher burden of late effects, not working/studying, being diagnosed with BT during adolescence, and reporting current depressive symptoms were significant predictors of lower HRQL.Conclusion Our results highlight that male survivors of childhood BT are at particular risk of impaired HRQL. Also, results point to the close relation between symptoms of depression and impaired HRQL in survivors of childhood BT which should be acknowledged by long-term follow-up care.

Find in a library

Supportive Care in Cancer (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Ljungman, Lisa, ...; Remes, Tiina; Westin, Elisabet ...; Huittinen, Alina; Lonnqvist, Tuula; Sirkia, Kirsti; show more...; Rantala, Heikki; Ojaniemi, Marja; Harila, Marika; Lahteenmaki, Pai ...; Arikoski, Pekka; Wikman, Anna; Harila-Saari, Ar ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cancer and Oncol ...

Articles in the publication: Supportive Care ...

By the university: Uppsala University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se

Health-related quality of life in long-term survivors of childhood brain tumors : a population-based cohort study

Subject headings

Keyword

Publication and Content Type

Find in a library

To the university's database

Find more in SwePub

Search outside SwePub