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Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant : A clinical and histopathological distinct entity showing epigenetic similarity with ATRT-MYC

Hasselblatt, Martin (author)
Univ Hosp Munster, Inst Neuropathol, Pottkamp 2, D-48149 Munster, Germany
Thomas, Christian (author)
Univ Hosp Munster, Inst Neuropathol, Pottkamp 2, D-48149 Munster, Germany
Federico, Aniello (author)
Hopp Childrens Canc Ctr KiTZ, Heidelberg, Germany.;German Canc Res Ctr, Div Paediat Neurooncol, Heidelberg, Germany.;German Canc Consortium DKTK, Heidelberg, Germany
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Bens, Susanne (author)
Ulm Univ, Inst Human Genet, Ulm, Germany.;Ulm Univ, Med Ctr, Ulm, Germany
Hellström, Mats (author)
Uppsala universitet,Experimentell och klinisk onkologi,Science for Life Laboratory, SciLifeLab
Casar Borota, Olivera (author)
Uppsala universitet,Science for Life Laboratory, SciLifeLab,Klinisk och experimentell patologi
Kordes, Uwe (author)
Univ Med Ctr, Dept Pediat Hematol & Oncol, Hamburg, Germany
Neumann, Julia E. (author)
Univ Med Ctr, Inst Neuropathol, Hamburg, Germany.;Univ Med Ctr Hamburg Eppendorf, Ctr Mol Neurobiol Hamburg ZM NH, Hamburg, Germany
Dottermusch, Matthias (author)
Univ Med Ctr, Inst Neuropathol, Hamburg, Germany.;Univ Med Ctr Hamburg Eppendorf, Ctr Mol Neurobiol Hamburg ZM NH, Hamburg, Germany
Rodriguez, Fausto J. (author)
Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA
Lo, Andrea C. (author)
British Columbia Canc, Radiat Oncol, Vancouver, BC, Canada.;Univ British Columbia, Vancouver, BC, Canada
Cheng, Sylvia (author)
Univ British Columbia, Dept Pediat, Div Hematol Oncol & BMT, Vancouver, BC, Canada
Hendson, Glenda (author)
BC Women & Childrens Hosp, Dept Pathol, Vancouver, BC, Canada
Hukin, Juliette (author)
Univ British Columbia, Dept Pediat, Div Hematol Oncol & BMT, Vancouver, BC, Canada
Hartmann, Christian (author)
Hannover Med Sch, Inst Pathol, Dept Neuropathol, Hannover, Germany
Koch, Arend (author)
Charite Univ Med Berlin, Dept Neuropathol, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Berlin, Germany
Capper, David (author)
Charite Univ Med Berlin, Dept Neuropathol, Berlin, Germany.;Free Univ Berlin, Berlin, Germany.;Humboldt Univ, Berlin, Germany.;German Canc Res Ctr, German Canc Consortium DKTK, Partner Site Berlin, Heidelberg, Germany
Siebert, Reiner (author)
Ulm Univ, Inst Human Genet, Ulm, Germany.;Ulm Univ, Med Ctr, Ulm, Germany
Paulus, Werner (author)
Univ Hosp Munster, Inst Neuropathol, Pottkamp 2, D-48149 Munster, Germany
Nemes, Karolina (author)
Univ Childrens Hosp Med Ctr Augsburg, Swabian Childrens Canc Ctr, Pediat & Adolescent Med, Augsburg, Germany.;EU RHAB Registry, Augsburg, Germany
Johann, Pascal D. (author)
Hopp Childrens Canc Ctr KiTZ, Heidelberg, Germany.;German Canc Res Ctr, Div Paediat Neurooncol, Heidelberg, Germany.;German Canc Consortium DKTK, Heidelberg, Germany.;Univ Childrens Hosp Med Ctr Augsburg, Swabian Childrens Canc Ctr, Pediat & Adolescent Med, Augsburg, Germany.;EU RHAB Registry, Augsburg, Germany
Fruehwald, Michael C. (author)
Univ Childrens Hosp Med Ctr Augsburg, Swabian Childrens Canc Ctr, Pediat & Adolescent Med, Augsburg, Germany.;EU RHAB Registry, Augsburg, Germany
Kool, Marcel (author)
Hopp Childrens Canc Ctr KiTZ, Heidelberg, Germany.;German Canc Res Ctr, Div Paediat Neurooncol, Heidelberg, Germany.;German Canc Consortium DKTK, Heidelberg, Germany.;Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
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Univ Hosp Munster, Inst Neuropathol, Pottkamp 2, D-48149 Munster, Germany Hopp Childrens Canc Ctr KiTZ, Heidelberg, Germany;German Canc Res Ctr, Div Paediat Neurooncol, Heidelberg, Germany.;German Canc Consortium DKTK, Heidelberg, Germany (creator_code:org_t)
2022-02-18
2022
English.
In: Neuropathology and Applied Neurobiology. - : John Wiley & Sons. - 0305-1846 .- 1365-2990. ; 48:4
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Low-grade diffusely infiltrative tumour (LGDIT), SMARCB1-mutant, is a histopathological distinct low-grade lesion encountered in older children and young adults that shows epigenetic similarity with ATRT-MYC and has the potential for malignant progression.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Medical Genetics (hsv//eng)

Keyword

atypical teratoid
rhabdoid tumour
central nervous system low-grade diffusely infiltrative tumour with INI1 deficiency
DNA methylation profiling
neuropathology

Publication and Content Type

ref (subject category)
art (subject category)

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