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The aorto-left vent...
The aorto-left ventricular tunnel from a fetal perspective : Original case series and literature review
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- van Nisselrooij, Amber E. L. (author)
- Leiden Univ, Dept Fetal Med & Obstet, Med Ctr, K6-35 Albinusdreef 2, NL-2333 ZA Leiden, Netherlands
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- Moon-Grady, Anita J. (author)
- Univ Calif San Francisco, Dept Pediat, Div Pediat Cardiol, San Francisco, CA USA
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- Wacker-Gussmann, Annette (author)
- German Heart Ctr Munich, Dept Pediat Cardiol & Congenital Heart Dis, Munich, Germany
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- Tomek, Viktor (author)
- Univ Hosp Motol, Childrens Heart Ctr Prague, Prague, Czech Republic
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- Malcic, Ivan (author)
- Zagreb Univ Hosp, Dept Childs Cardiol, Zagreb, Croatia
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- Grzyb, Agnieszka (author)
- Ctr Postgrad Med Educ, Dept Perinatal Cardiol & Congenital Anomalies, Warsaw, Poland.;Childrens Mem Hlth Inst, Dept Cardiol, Warsaw, Poland
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- Pavlova, Anna (author)
- Ukrainian Childrens Cardiac Ctr, Dept Cardiol, Kiev, Ukraine
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- Kazamia, Kalliopi (author)
- Karolinska Institutet,Uppsala universitet,Institutionen för kvinnors och barns hälsa,Karolinska Univ Hosp, Childrens Heart Ctr Stockholm Uppsala, Stockholm, Sweden
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- Thakur, Varsha (author)
- Hosp Sick Children, Labatt Family Heart Ctr, Div Cardiol, Toronto, ON, Canada
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- Sinkovskaya, Elena (author)
- Eastern Virginia Med Sch, Dept Obstet & Gynecol, Norfolk, VA 23501 USA
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- Ten Harkel, A. Derk Jan (author)
- Leiden Univ, Dept Fetal Med & Obstet, Med Ctr, K6-35 Albinusdreef 2, NL-2333 ZA Leiden, Netherlands
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- Haak, Monique C. (author)
- Leiden Univ, Dept Fetal Med & Obstet, Med Ctr, K6-35 Albinusdreef 2, NL-2333 ZA Leiden, Netherlands
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(creator_code:org_t)
- 2022-01-22
- 2022
- English.
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In: Prenatal Diagnosis. - : John Wiley & Sons. - 0197-3851 .- 1097-0223. ; 42:2, s. 267-277
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Abstract
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- Introduction Aorto-left ventricular tunnel (ALVT) accounts for <0.1% of congenital heart defects. Evidence on the prognosis from a fetal perspective is limited. With this retrospective international case series, we provide information on the outcome of fetuses with ALVT.Methods All members of the Association for European Pediatric and Congenital Cardiology's (AEPC) fetal working group and fetal medicine units worldwide were invited for participation. We observed antenatal parameters, neonatal outcome and postnatal follow-up. Additionally, a systematic search of the literature was performed.Results Twenty fetuses with ALVT were identified in 10 participating centers (2001-2019). Fetal echocardiographic characteristics of ALVT included an increased cardiac-thorax ratio (95%), left ventricular end-diastolic diameter (90%) and a dysplastic aortic valve (90%). Extracardiac malformations were rare (5%). Eight fetuses died at a median gestational age (GA) of 21 + 6 weeks (range, 19-24): all showed signs of hydrops prior to 24 weeks or at autopsy. All others (60%, 12/2) were live-born (median GA 38 + 4, range 37-40), underwent surgery and were alive at last follow up (median 3.2 years, range 0.1-17). The literature reported 22 ALVT fetuses with similar outcome.Conclusions In the absence of fetal hydrops, ALVT carries a good prognosis. Fetuses who survive to 24 weeks without hydrops are likely to have a good outcome.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
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van Nisselrooij, ...
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Moon-Grady, Anit ...
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Wacker-Gussmann, ...
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Tomek, Viktor
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Malcic, Ivan
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Grzyb, Agnieszka
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Pavlova, Anna
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Kazamia, Kalliop ...
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Thakur, Varsha
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Sinkovskaya, Ele ...
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Ten Harkel, A. D ...
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Haak, Monique C.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Obstetrics Gynae ...
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Prenatal Diagnos ...
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Uppsala University
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Karolinska Institutet