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Clinical standards ...
Clinical standards for the dosing and management of TB drugs
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- Alffenaar, J. W. C. (author)
- Univ Sydney, Sydney Inst Infect Dis, Sydney, NSW, Australia.;Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia.;Westmead Hosp, Sydney, NSW, Australia
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- Stocker, S. L. (author)
- Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia.;St Vincents Hosp, Dept Clin Pharmacol & Toxicol, Sydney, NSW, Australia.;Univ NSW, St Vincents Clin Campus, Kensington, NSW, Australia,Univ Texas Hlth Sci Ctr Tyler, TX USA
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- Forsman, L. Davies (author)
- Karolinska Institutet,Karolinska Inst, Sweden; Karolinska Univ Hosp, Sweden
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show more...
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- Garcia-Prats, A. (author)
- Stellenbosch Univ, Desmond Tutu TB Ctr, Dept Paediat & Child Hlth, Tygerberg, South Africa.;Univ Wisconsin, Dept Pediat, Madison, WI USA,Grodno State Med Univ, BELARUS
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- Heysell, S. K. (author)
- Univ Virginia, Div Infect Dis & Int Hlth, Charlottesville, VA USA
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- Aarnoutse, R. E. (author)
- Radboud Univ Nijmegen Med Ctr, Radboud Inst Hlth Sci, Dept Pharm, Nijmegen, Netherlands.;Radboud Univ Nijmegen Med Ctr, Radboudumc Ctr Infect Dis, Nijmegen, Netherlands,Univ Padjadjaran, Indonesia
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- Akkerman, O. W. (author)
- Univ Groningen, Univ Med Ctr Groningen, Dept Pulm Dis & TB, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, TB Ctr Beatrixoord, Haren, Netherlands
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- Aleksa, A. (author)
- Grodno State Med Univ, Educ Inst, Grodno, BELARUS,Fundacao Oswaldo Cruz, Brazil,Stellenbosch Univ, South Africa,Univ Liverpool, England,Univ Florida, FL USA,Republican Res & Pract Ctr Pulmonol & TB, BELARUS,Univ Virginia, VA USA
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- van Altena, R. (author)
- Asian Harm Reduct Network AHRN, Yangon, Myanmar.;Med Act Myanmar MAM, Yangon, Myanmar
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- de Onata, W. Arrazola (author)
- Belgian Sci Inst Publ Hlth, Belgian Lung & TB Assoc, Brussels, Belgium
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- Bhavani, P. K. (author)
- Indian Council Med Res Natl Inst Res TB, Int Ctr Excellence Res, Chennai, Tamil Nadu, India
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- Van't Boveneind-Vrubleuskaya, N. (author)
- Univ Groningen, Univ Med Ctr Groningen, Dept Clin Pharm & Pharmacol, Groningen, Netherlands.;Metropolitan Publ Hlth Serv, Dept Publ Hlth TB Control, The Hague, Netherlands
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- Carvalho, A. C. C. (author)
- Fundacao Oswaldo Cruz, Lab Inovacoes Terapias Ensino & Bioprod LITEB, Inst Oswaldo Cruz, Rio De Janeiro, RJ, Brazil
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- Centis, R. (author)
- Ist Ricovero & Cura Carattere Sci IRCCS, Ist Clin Sci Maugeri, Serv Epidemiol Clin Malattie Resp, Tradate, Italy
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- Chakaya, J. M. (author)
- Kenyatta Univ, Dept Med Therapeut & Dermatol, Nairobi, Kenya.;Univ Liverpool Liverpool Sch Trop Med, Dept Clin Sci, Liverpool, Merseyside, England
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- Cirillo, D. M. (author)
- IRCCS San Raffaele Sci Inst, Div Immunol Transplantat & Infect Dis, Emerging Bacterial Pathogens Unit, Milan, Italy
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- Cho, J. G. (author)
- Univ Sydney, Sydney Inst Infect Dis, Sydney, NSW, Australia.;Westmead Hosp, Sydney, NSW, Australia.;Parramatta Chest Clin, Parramatta, NSW, Australia
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- Ambrosio, L. D. (author)
- Publ Hlth Consulting Grp, Lugano, Switzerland
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- Dalcolmo, M. P. (author)
- Funda Oswaldo Cruz Fiocruz, Reference Ctr Helio Fraga, Rio De Janeiro, RJ, Brazil
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- Denti, P. (author)
- Univ Cape Town, Dept Med, Div Clin Pharmacol, Cape Town, South Africa
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- Dheda, K. (author)
- Univ Cape Town, Ctr Lung Infect & Immun, Div Pulmonol, Dept Med, Cape Town, South Africa.;Univ Cape Town, UCT Lung Inst, Cape Town, South Africa.;Univ Cape Town Lung Inst, Cape Town, South Africa.;South African MRC Ctr Study Antimicrobial Resista, Cape Town, South Africa.;London Sch Hyg & Trop Med, Fac Infect & Trop Dis, Dept Immunol & Infect, London, England
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- Fox, G. J. (author)
- Univ Sydney, Fac Med & Hlth, Sydney Med Sch, Sydney, NSW, Australia.;Woolcock Inst Med Res, Glebe, NSW, Australia
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- Hesseling, A. C. (author)
- Stellenbosch Univ, Desmond Tutu TB Ctr, Dept Paediat & Child Hlth, Tygerberg, South Africa
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- Kim, H. Y. (author)
- Univ Sydney, Sydney Inst Infect Dis, Sydney, NSW, Australia.;Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia.;Westmead Hosp, Sydney, NSW, Australia
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- Koser, C. U. (author)
- Univ Cambridge, Dept Genet, Cambridge, England
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- Marais, B. J. (author)
- Univ Sydney, Sydney Inst Infect Dis, Sydney, NSW, Australia.;Childrens Hosp Westmead, Dept Infect Dis & Microbiol, Westmead, NSW, Australia
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- Margineanu, I (author)
- Univ Groningen, Univ Med Ctr Groningen, Dept Clin Pharm & Pharmacol, Groningen, Netherlands
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- Martson, A. G. (author)
- Univ Liverpool, Inst Translat Med, Dept Mol & Clin Pharmacol, Liverpool, Merseyside, England
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- Torrico, M. Munoz (author)
- Inst Nacl Enfermedades Resp, Clin TB, Ciudad De Mexico, Mexico
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- Nataprawira, H. M. (author)
- Univ Padjadjaran, Hasan Sadikin Hosp, Fac Med, Dept Child Hlth,Div Paediat Respirol, Bandung, Indonesia
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- Ong, C. W. M. (author)
- Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Infect Dis Translat Res Programme, Singapore, Singapore.;Natl Univ Singapore, Inst Hlth Innovat & Technol iHealthtech, Singapore, Singapore.;Natl Univ Singapore Hosp, Dept Med, Div Infect Dis, Singapore, Singapore
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- Otto-Knapp, R. (author)
- German Cent Comm TB DZK, Berlin, Germany
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- Peloquin, C. A. (author)
- Univ Florida, Infect Dis Pharmacokinet Lab, Pharmacitherapy & Translat Res, Coll Pharm, Gainesville, FL USA
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- Silva, D. R. (author)
- Univ Fed Rio Grande do Sul, Fac Med, Porto Alegre, RS, Brazil
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- Ruslami, R. (author)
- Univ Padjadjaran, Fac Med, TB HIV Res Ctr, Bandung, Indonesia.;Univ Padjadjaran, Fac Med, Dept Biomed Sci, Div Pharmacol & Therapy, Bandung, Indonesia,Univ Calif San Francisco, CA USA,Natl Inst TB & Resp Dis, India
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- Santoso, P. (author)
- Univ Padjadjaran, Fac Med, Dept Internal Med, Div Respirol & Crit Care,Hasan Sadikin Gen Hosp, Bandung, Indonesia
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- Savic, R. M. (author)
- Univ Calif San Francisco, Sch Pharm, Dept Bioengn & Therapeut Sci, Div Pulm & Crit Care Med, San Francisco, CA USA.;Univ Calif San Francisco, Sch Med, Div Pulm & Crit Care Med, Dept Bioengn & Therapeut Sci, San Francisco, CA USA
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- Singla, R. (author)
- Natl Inst TB & Resp Dis, Dept TB & Resp Dis, New Delhi, India
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- Svensson, Elin, 1985- (author)
- Uppsala universitet,Institutionen för farmaci,Radboud Univ Nijmegen Med Ctr, Radboud Inst Hlth Sci, Dept Pharm, Nijmegen, Netherlands.;Radboud Univ Nijmegen Med Ctr, Radboudumc Ctr Infect Dis, Nijmegen, Netherlands,Radboud Univ Nijmegen Med Ctr, Netherlands; Uppsala Univ, Sweden
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- Skrahina, A. (author)
- Republican Res & Pract Ctr Pulmonol & TB, Minsk, BELARUS
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- van Soolingen, D. (author)
- Natl Inst Publ Hlth & Environm, TB Reference Lab RIVM, Bilthoven, Netherlands
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- Srivastava, S. (author)
- Univ Texas Hlth Sci Ctr Tyler, Dept Pulm Immunol, Tyler, TX USA,Queen Mary Univ London, England,Kilimanjaro Christian Med Univ Coll, Tanzania; Kibongoto Infect Dis Hosp, Tanzania
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- Tadolini, M. (author)
- IRCCS Azienda Osped Univ Bologna, Infect Dis Unit, Bologna, Italy.;Alma Mater Studiorum Univ Bologna, Dept Med & Surg Sci, Bologna, Italy
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- Tiberi, S. (author)
- Queen Mary Univ London, Barts & London Sch Med & Dent, Blizard Inst, London, England
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- Thomas, T. A. (author)
- Univ Virginia, Div Infect Dis & Int Hlth, Charlottesville, VA USA
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- Udwadia, Z. F. (author)
- PD Hinduja Natl Hosp & Med Res Ctr, Mumbai, Maharashtra, India
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- Vu, D. H. (author)
- Hanoi Univ Pharm, Natl Drug Informat & Adverse Drug React Monitorin, Hanoi, Vietnam
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- Zhang, W. (author)
- Fudan Univ, Huashan Hosp, Shanghai Med Coll,Shanghai Key Lab Infect Dis & B, Natl Med Ctr Infect Dis,Dept Infect Dis, Shanghai, Peoples R China
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- Mpagama, S. G. (author)
- Kilimanjaro Christian Med Univ Coll, Moshi, Tanzania.;Kibongoto Infect Dis Hosp, Siha, Kilimanjaro, Tanzania
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- Schön, Thomas (author)
- Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Infektionskliniken i Östergötland,Kalmar Cty Hosp, Sweden
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- Migliori, G. B. (author)
- Grodno State Med Univ, Educ Inst, Grodno, BELARUS
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Univ Sydney, Sydney Inst Infect Dis, Sydney, NSW, Australia;Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia.;Westmead Hosp, Sydney, NSW, Australia Univ Sydney, Sch Pharm, Fac Med & Hlth, Sydney, NSW, Australia.;St Vincents Hosp, Dept Clin Pharmacol & Toxicol, Sydney, NSW, Australia.;Univ NSW, St Vincents Clin Campus, Kensington, NSW, Australia (creator_code:org_t)
- Paris, France : International Union Against Tuberculosis and Lung Disease, 2022
- 2022
- English.
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In: The International Journal of Tuberculosis and Lung Disease. - Paris, France : International Union Against Tuberculosis and Lung Disease. - 1027-3719 .- 1815-7920. ; 26:6, s. 483-
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Abstract
Subject headings
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- Background: Optimal drug dosing is important to ensure adequate response to treatment, prevent development of drug resistance and reduce drug toxicity. The aim of these clinical standards is to provide guidance on 'best practice' for dosing and management of TB drugs.Methods: A panel of 57 global experts in the fields of microbiology, pharmacology and TB care were identified; 51 participated in a Delphi process. A 5-point Likert scale was used to score draft standards. The final document represents the broad consensus and was approved by all participants.Results: Six clinical standards were defined: Standard 1, defining the most appropriate initial dose for TB treatment; Standard 2, identifying patients who may be at risk of sub-optimal drug exposure; Standard 3, identifying patients at risk of developing drug-related toxicity and how best to manage this risk; Standard 4, identifying patients who can benefit from therapeutic drug monitoring (TDM); Standard 5, highlighting education and counselling that should be provided to people initiating TB treatment; and Standard 6, providing essential education for healthcare professionals. In addition, consensus research priorities were identified.Conclusion: This is the first consensus-based Clinical Standards for the dosing and management of TB drugs to guide clinicians and programme managers in planning and implementation of locally appropriate measures for optimal person-centred treatment to improve patient care.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- tuberculosis
- pharmacokinetics
- pharmacodynamics
- adverse drug reaction
- management
- dosing
Publication and Content Type
- vet (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Alffenaar, J. W. ...
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Stocker, S. L.
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Forsman, L. Davi ...
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Garcia-Prats, A.
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Heysell, S. K.
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Aarnoutse, R. E.
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show more...
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Akkerman, O. W.
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Aleksa, A.
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van Altena, R.
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de Onata, W. Arr ...
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Bhavani, P. K.
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Van't Boveneind- ...
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Carvalho, A. C. ...
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Centis, R.
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Chakaya, J. M.
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Cirillo, D. M.
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Cho, J. G.
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Ambrosio, L. D.
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Dalcolmo, M. P.
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Denti, P.
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Dheda, K.
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Fox, G. J.
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Hesseling, A. C.
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Kim, H. Y.
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Koser, C. U.
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Marais, B. J.
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Margineanu, I
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Martson, A. G.
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Torrico, M. Muno ...
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Nataprawira, H. ...
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Ong, C. W. M.
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Otto-Knapp, R.
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Peloquin, C. A.
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Silva, D. R.
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Ruslami, R.
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Santoso, P.
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Savic, R. M.
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Singla, R.
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Svensson, Elin, ...
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Skrahina, A.
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van Soolingen, D ...
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Srivastava, S.
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Tadolini, M.
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Tiberi, S.
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Thomas, T. A.
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Udwadia, Z. F.
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Vu, D. H.
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Zhang, W.
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Mpagama, S. G.
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Schön, Thomas
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Migliori, G. B.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Pharmacology and ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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The Internationa ...
- By the university
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Uppsala University
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Karolinska Institutet
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Linköping University