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Secondary Le Fort I...
Secondary Le Fort III after Early Fronto-Facial Monobloc Normalizes Sleep Apnea in Faciocraniosynostosis : A Cohort Study
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- Haber, Samer E. (author)
- Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.
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- Leikola, Junnu (author)
- Univ Helsinki, Toolo Hosp,Cent Hosp, Cleft Palate & Craniofacial Ctr, Dept Plast Surg, POB 266, FI-00029 Helsinki, Finland.
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- Nowinski, Daniel (author)
- Uppsala universitet,Plastikkirurgi
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- Fauroux, Brigitte (author)
- Univ Sorbonne Paris Cite, Serv Ventilat Noninvas & Sommeil delEnfant, Paris, France.;Univ Sorbonne Paris Cite, Assistance Publ Hop Paris, Hop Univ Necker Enfants Malad, Paris, France.;Univ Sorbonne Paris Cite, VIFASOM Vigilance Fatigue Sommeilet St Publ EA7330, Paris, France.;Univ Paris 05, Univ Sorbonne Paris C, Descartes, Paris, France.
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- Morisseau-Durand, Marie-Paule (author)
- Univ Paris 05, Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Otorhinolaryngol Pediat, Paris, France.;Univ Paris 05, Ctr Reference Malad Rares MALO, Filiere Malad Rares TeteCou, Paris, France.;Univ Paris, Univ Paris Descartes, Paris, France.
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- Paternoster, Giovanna (author)
- Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.
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- Khonsari, Roman H. (author)
- Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.;Univ Paris, Hop Necker Enfants Malad, Assistance Publ Hop Paris, Serv Chirurg maxillofaciale & Chirurg plast, Paris, France.
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- Arnaud, Eric (author)
- Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France.;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France.;Clin Marcel Sembat, F-92100 Boulogne, France.;Hop Necker Enfants Malad, Serv Neurochirurg Pediat, Unite fonct Chirurg craniofaciale, 34 Ave Eylau, F-75116 Paris, France.
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Univ Paris, Assistance Publ Hop Paris, Hop Necker Enfants Malad, Serv Neurochirurg Pediat,Unite Fonctionnelle Chiru, Paris, France;Univ Paris, Ctr Reference Malad Rares CRANIOST, Filiere Malad Rares Tete Cou, Paris, France. Univ Helsinki, Toolo Hosp,Cent Hosp, Cleft Palate & Craniofacial Ctr, Dept Plast Surg, POB 266, FI-00029 Helsinki, Finland. (creator_code:org_t)
- Elsevier, 2022
- 2022
- English.
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In: Journal of Plastic, Reconstructive & Aesthetic Surgery. - : Elsevier. - 1748-6815 .- 1878-0539. ; 75:8, s. 2706-2718
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background: This study aims to assess the improvement of sleep apnea after sec-ondary Le Fort III facial advancement with distraction (LF3) in faciocraniosynostosis (FCS) pa-tients with sleep apnea who have previously undergone fronto-facial monobloc advancement (FFMBA) with distraction.Methods: Patients having undergone secondary LF3 were selected from a cohort of FCS pa-tients with documented sleep apnea who had previously undergone fronto-facial monobloc advancement. Patient charts and polysomnographic records were reviewed. Apnea-hypopnea index (AHI) was recorded before and at least 6 months after secondary LF3. The primary out-come was normalization of AHI (less than 5/h was considered normal). Hierarchical multilevel analysis was performed to predict postoperative AHI evolution.Results: Seventeen patients underwent a secondary LF3, 7.0 +/- 3.9 years after the primary FFMBA. The mean age was 9.6 +/- 3.9 years. A total of 15 patients (88%) normalized their AHI. Two of four patients were decannulated (50%). There was a statistically significant decrease in AHI (preoperative AHI 21.5/h vs. 3.9/h postoperatively, p = 0.003). Hierarchic multilevel mod-eling showed progressive AHI decrease postoperatively.Conclusion: Secondary LF3 improves residual or relapsing sleep apnea in FCS patients who have previously had FFMBA.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Keyword
- Syndromic craniosynostosis
- faciocraniosynostosis
- facial advancement
- distraction
- sleep apnea
- craniofacial osteotomy
- FGFR
- AHI
Publication and Content Type
- ref (subject category)
- art (subject category)
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