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The Microbiology of...
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Sorelius, KarlUppsala universitet,Institutionen för kirurgiska vetenskaper,Rigshosp, Dept Vasc Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.
(author)
The Microbiology of Infective Native Aortic Aneurysms in a Population-Based Setting
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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Elsevier,2022
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-488548
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-488548URI
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https://doi.org/10.1016/j.avsg.2021.06.039DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:151070544URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Objective: The aim was to describe the microbiology of surgically treated infective native (mycotic) aortic aneurysms (INAAs), and associated survival and development of infection-related complications (IRCs). Methods: Data were pooled from 2 nationwide studies on surgically treated patients with INAAs in Sweden, between 1994 - 2016. Patients were grouped and analyzed according to culture results: 1) Staphylococcus aureus, 2) Streptococcus species (sp.), 3) Salmonella sp., 4) Enterococcus sp., 5) Gram-negative intestinal bacteria, 6) Other sp. (all other species found in culture), and 7) Negative cultures. Results: A sum of 182 patients were included, mean age 71 years (standard deviation; SD: 8.9). The median follow-up was 50.3 months (range 0 - 360). 128 (70.3%) patients had positive blood and/or tissue culture; Staphylococcus aureus n = 38 (20.9%), Streptococcus sp. n = 37 (20.3%), Salmonella sp. n = 19 (10.4%), Enterococcus sp. n = 16 (8.8%), Gram-negative intestinal bacteria n = 6, (3.3%), Other sp. n = 12 (6.6%) and Negative cultures n = 54 (29.7%). The estimated survival for the largest groups at 2-years after surgery was: Staphylococcus aureus 62% (95% Confidence interval 53.9 - 70.1), Streptococcus sp. 74.7% (67.4 - 82.0), Salmonella sp. 73.7% (63.6 - 83.8), Enterococcus sp. 61.9% (49.6 - 74.2), and Negative cultures 89.8% (85.5 - 94.1), P =.051. There were 37 IRCs (20.3%), and 19 (51.4%) were fatal, the frequency was insignificant between the groups. The majority of IRCs, 30/37 (81%), developed during the first postoperative year. Conclusion: In this assessment of microbiological findings of INAAs in Sweden, 50% of the pathogens were Staphylococcus aureus, Streptococcus sp., or Salmonella sp.. The overall 20%-frequency of IRCs, and its association with high mortality, motivates long-term antibiotic treatment regardless of microbial findings.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Wanhainen, AndersUppsala universitet,Kärlkirurgi(Swepub:uu)anwan103
(author)
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Furebring, MiaUppsala universitet,Infektionsmedicin(Swepub:uu)miafureb
(author)
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Mani, Kevin,1975-Uppsala universitet,Kärlkirurgi(Swepub:uu)kevma940
(author)
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Resch, T.Rigshosp, Dept Vasc Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.
(author)
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Hultgren, R.Karolinska Institutet,Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.,Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden.
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Wahlgren, C. M.Karolinska Institutet,Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.,Reg Hosp Sundsvall, Dept Surg, Sundsvall, Sweden.
(author)
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Roos, H.Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden.
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Ojersjo, A.Kalmar Hosp, Dept Surg, Kalmar, Sweden.
(author)
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Lindström, DavidUppsala universitet,Kärlkirurgi(Swepub:uu)davli314
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Vaccarino, R.Skane Univ Hosp, Vasc Ctr, Malmö, Sweden.
(author)
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Arvidsson, B.Linköping Univ, Dept Thorac & Vasc Surg, Linköping, Sweden.;Linköping Univ, Dept Med & Hlth Sci, Linköping, Sweden.,Västerås Hosp, Dept Vasc Surg, Västerås, Sweden.
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Bilos, L.Örebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Örebro, Sweden.
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Pirouzram, A.Örebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Örebro, Sweden.
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Arnerlov, C.Umeå Univ Hosp, Dept Surg & Perioperat Sci, Surg, Umeå, Sweden.
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Simo, G.Cent Hosp Karlstad, Dept Surg, Karlstad, Sweden.
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Svensson, M.Falun Cent Hosp, Dept Surg, Falun, Sweden.,NU Hospitalgrp, Dept Surg, Trollhättan Uddevalla, Sweden.
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Magnusson, J.Helsingborg Hosp, Dept Surg, Helsingborg, Sweden.
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Astrand, H.Jönköping Hosp, Dept Surg, Jönköping, Sweden.
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Palm, M.Sunderby Hosp, Dept Surg, Sunderbyn, Sweden.
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Holsti, M.Umeå Univ Hosp, Dept Surg & Perioperat Sci, Surg, Umeå, Sweden.
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Mellander, S.NU Hospitalgrp, Dept Surg, Trollhättan Uddevalla, Sweden.
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Korman, D.Östersunds Hosp, Dept Surg, Östersund, Sweden.,Gävle Cent Hosp, Dept Surg, Gävle, Sweden.
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Djavani-Gidlund, K.Gävle Cent Hosp, Dept Surg, Gävle, Sweden.
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Huss, M.Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.
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Bertszel, A.Västerås Hosp, Dept Vasc Surg, Västerås, Sweden.
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Docter, M.Hudiksvall Hosp, Dept Surg, Hudiksvall, Sweden.
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Drott, C.Borås Hosp, Dept Surg, Borås, Sweden.
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Nelzen, O.Skaraborg Hosp, Dept Vasc Surg, Skoevde, Sweden.
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Wetterling, T.Kristianstad Hosp, Dept Surg, Kristianstad, Sweden.
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Chu, M.Reg Hosp Sundsvall, Dept Surg, Sundsvall, Sweden.
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Gilgen, N-PKarolinska Institutet,Malar Hosp, Dept Surg, Eskilstuna, Sweden.,Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden.;Soder Sjukhuset, Unit Vasc Surg, Dept Surg, Stockholm, Sweden.
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Gillgren, P.Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden.;Soder Sjukhuset, Unit Vasc Surg, Dept Surg, Stockholm, Sweden.
(author)
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Uppsala universitetInstitutionen för kirurgiska vetenskaper
(creator_code:org_t)
Related titles
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In:Annals of Vascular Surgery: Elsevier78, s. 112-1220890-50961615-5947
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- By the author/editor
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Sorelius, Karl
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Wanhainen, Ander ...
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Furebring, Mia
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Mani, Kevin, 197 ...
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Resch, T.
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Hultgren, R.
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Wahlgren, C. M.
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Roos, H.
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Ojersjo, A.
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Lindström, David
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Vaccarino, R.
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Arvidsson, B.
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Bilos, L.
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Pirouzram, A.
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Arnerlov, C.
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Simo, G.
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Svensson, M.
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Magnusson, J.
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Astrand, H.
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Palm, M.
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Holsti, M.
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Mellander, S.
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Korman, D.
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Djavani-Gidlund, ...
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Huss, M.
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Bertszel, A.
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Docter, M.
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Drott, C.
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Nelzen, O.
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Wetterling, T.
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Chu, M.
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Gilgen, N-P
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Gillgren, P.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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MEDICAL AND HEAL ...
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and Infectious Medic ...
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Annals of Vascul ...
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Uppsala University
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Karolinska Institutet