Search: onr:"swepub:oai:DiVA.org:uu-488572" > Geographic disparit...
Fältnamn | Indikatorer | Metadata |
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000 | 05781naa a2200553 4500 | |
001 | oai:DiVA.org:uu-488572 | |
003 | SwePub | |
008 | 221118s2022 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4885722 URI |
024 | 7 | a https://doi.org/10.1016/j.ijcard.2022.08.0132 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Kageyama, Shigetakau Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.4 aut |
245 | 1 0 | a Geographic disparity in 10-year mortality after coronary artery revascularization in the SYNTAXES trial |
264 | 1 | b Elsevier,c 2022 |
338 | a print2 rdacarrier | |
520 | a Aims: To investigate geographic disparity in long-term mortality following revascularization in patients with complex coronary artery disease (CAD).Methods and results: The SYNTAXES trial randomized 1800 patients with three-vessel and/or left main CAD to percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and assessed their survival at 10 years. Patients were stratified according to the region of recruitment: North America (N-A, n = 245), Eastern Europe (E-E, n = 189), Northern Europe (N-E, n = 425), Southern Europe (S-E, n = 263), and Western Europe (W-E, n = 678), which also served as the reference group. Compared to W-E, patients were younger in E-E (62 vs 65 years, p < 0.001), and less frequently male in N-A (65.3% vs 79.6%, p < 0.001). Diabetes (16.0% vs 25.4%, p < 0.001) and peripheral vascular disease (6.8% vs 10.9%, p = 0.025) were less frequent in N-E than W-E. Ejection fraction was highest in W-E (62% vs 56%, p < 0.001). Compared to W-E, the mean anatomic SYNTAX score was higher in S-E (29 vs 31, p = 0.008) and lower in N-A (26, p < 0.001). Crude ten-year mortality was similar in N-A (31.6%), and W-E (30.7%), and significantly lower in E-E (22.5%, p = 0.041), N-E (21.9%, p = 0.003) and S-E (22.0%, p = 0.014). Compared to W-E, adjusted mortality in N-E (HR 0.85, p = 0.019) and S-E (HR 0.72, p = 0.043) remain significantly lower after adjustment for pre-and peri-procedural factors, but no significant interaction (Pinteraction = 0.728) between region and modality of revascularization was seen.Conclusion: In the era of globalization, knowledge, and understanding of geographic disparity are of paramount importance for the correct interpretation of global studies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
653 | a Geographic disparity | |
653 | a Revascularization | |
653 | a Complex coronary artery disease | |
653 | a Ten-year mortality | |
700 | 1 | a Serruys, Patrick W.u Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.;Imperial Coll London, Natl Heart & Lung Inst, London, England.4 aut |
700 | 1 | a Garg, Scotu Royal Blackburn Hosp, Dept Cardiol, Blackburn, Lancs, England.4 aut |
700 | 1 | a Ninomiya, Kaiu Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.4 aut |
700 | 1 | a Masuda, Shinichirou Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.4 aut |
700 | 1 | a Kotoku, Nozomiu Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.4 aut |
700 | 1 | a Colombo, Antoniou Humanitas Univ, Dept Biomed Sci, Pieve Emanuele Milan, Italy.;Humanitas Clin & Res Ctr IRCCS, Rozzano Milan, Italy.4 aut |
700 | 1 | a Mack, Michael J.u Baylor Univ, Med Ctr, Dept Cardiothorac Surg, Dallas, TX USA.4 aut |
700 | 1 | a Banning, Adrian P.u Oxford Univ Hosp, John Radcliffe Hosp, Dept Cardiol, Oxford, England.4 aut |
700 | 1 | a Morice, Marie-Claudeu Hop Prive Jacques Cartier, Gen Sante Massy, Dept Cardiol, Massy, France.4 aut |
700 | 1 | a Witkowski, Adamu Natl Inst Cardiol, Dept Intervent Cardiol & Angiol, Warsaw, Poland.4 aut |
700 | 1 | a Curzen, Nicku Univ Southampton, Fac Med, Southampton, Hants, England.;Univ Hosp Southampton NHS Trust, Cardiothorac Unit, Southampton, Hants, England.4 aut |
700 | 1 | a Burzotta, Francescou Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli IRCCS, Inst Cardiol, Rome, Italy.4 aut |
700 | 1 | a James, Stefan,d 1964-u Uppsala universitet,Institutionen för medicinska vetenskaper4 aut0 (Swepub:uu)stjam367 |
700 | 1 | a van Geuns, Robert-Janu Radboud Univ Nijmegen, Dept Cardiol, Med Ctr, Nijmegen, Netherlands.4 aut |
700 | 1 | a Davierwala, Piroze M.u Univ Toronto, Dept Surg, Toronto, ON, Canada.;Toronto Gen Hosp, Peter Munk Cardiac Ctr, Div Cardiovasc Surg, Toronto, ON, Canada.;Univ Hlth Network, Toronto, ON, Canada.4 aut |
700 | 1 | a Holmes, David R., Jr.u Mayo Clin, Dept Cardiovasc Dis & Internal Med, Rochester, MN USA.4 aut |
700 | 1 | a Wood, David A.u Imperial Coll London, Natl Heart & Lung Inst, London, England.;Natl Univ Ireland, Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland.4 aut |
700 | 1 | a McEvoy, John Williamu Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.;Natl Univ Ireland, Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland.4 aut |
700 | 1 | a Onuma, Yoshinobuu Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.4 aut |
710 | 2 | a Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.b Natl Univ Ireland, Dept Cardiol, Galway NUIG, Galway, Ireland.;Imperial Coll London, Natl Heart & Lung Inst, London, England.4 org |
773 | 0 | t International Journal of Cardiologyd : Elsevierg 368, s. 28-38q 368<28-38x 0167-5273x 1874-1754 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-488572 |
856 | 4 8 | u https://doi.org/10.1016/j.ijcard.2022.08.013 |
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