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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00010117naa a2201789 4500
001oai:DiVA.org:uu-489776
003SwePub
008221205s2022 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4897762 URI
024a https://doi.org/10.1001/jama.2022.189312 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Wulf Hanson, Sarah4 aut
2451 0a Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021
264 1b American Medical Association (AMA),c 2022
338 a print2 rdacarrier
520 a IMPORTANCE: Some individuals experience persistent symptoms after initial symptomatic SARS-CoV-2 infection (often referred to as Long COVID).OBJECTIVE: To estimate the proportion of males and females with COVID-19, younger or older than 20 years of age, who had Long COVID symptoms in 2020 and 2021 and their Long COVID symptom duration.DESIGN, SETTING, AND PARTICIPANTS: Bayesian meta-regression and pooling of 54 studies and 2 medical record databases with data for 1.2 million individuals (from 22 countries) who had symptomatic SARS-CoV-2 infection. Of the 54 studies, 44 were published and 10 were collaborating cohorts (conducted in Austria, the Faroe Islands, Germany, Iran, Italy, the Netherlands, Russia, Sweden, Switzerland, and the US). The participant data were derived from the 44 published studies (10 501 hospitalized individuals and 42 891 nonhospitalized individuals), the 10 collaborating cohort studies (10 526 and 1906), and the 2 US electronic medical record databases (250 928 and 846 046). Data collection spanned March 2020 to January 2022.EXPOSURES: Symptomatic SARS-CoV-2 infection.MAIN OUTCOMES AND MEASURES: Proportion of individuals with at least 1 of the 3 self-reported Long COVID symptom clusters (persistent fatigue with bodily pain or mood swings; cognitive problems; or ongoing respiratory problems) 3 months after SARS-CoV-2 infection in 2020 and 2021, estimated separately for hospitalized and nonhospitalized individuals aged 20 years or older by sex and for both sexes of nonhospitalized individuals younger than 20 years of age.RESULTS: A total of 1.2 million individuals who had symptomatic SARS-CoV-2 infection were included (mean age, 4-66 years; males, 26%-88%). In the modeled estimates, 6.2% (95% uncertainty interval [UI], 2.4%-13.3%) of individuals who had symptomatic SARS-CoV-2 infection experienced at least 1 of the 3 Long COVID symptom clusters in 2020 and 2021, including 3.2% (95% UI, 0.6%-10.0%) for persistent fatigue with bodily pain or mood swings, 3.7% (95% UI, 0.9%-9.6%) for ongoing respiratory problems, and 2.2% (95% UI, 0.3%-7.6%) for cognitive problems after adjusting for health status before COVID-19, comprising an estimated 51.0% (95% UI, 16.9%-92.4%), 60.4% (95% UI, 18.9%-89.1%), and 35.4% (95% UI, 9.4%-75.1%), respectively, of Long COVID cases. The Long COVID symptom clusters were more common in women aged 20 years or older (10.6% [95% UI, 4.3%-22.2%]) 3 months after symptomatic SARS-CoV-2 infection than in men aged 20 years or older (5.4% [95% UI, 2.2%-11.7%]). Both sexes younger than 20 years of age were estimated to be affected in 2.8% (95% UI, 0.9%-7.0%) of symptomatic SARS-CoV-2 infections. The estimated mean Long COVID symptom cluster duration was 9.0 months (95% UI, 7.0-12.0 months) among hospitalized individuals and 4.0 months (95% UI, 3.6-4.6 months) among nonhospitalized individuals. Among individuals with Long COVID symptoms 3 months after symptomatic SARS-CoV-2 infection, an estimated 15.1% (95% UI, 10.3%-21.1%) continued to experience symptoms at 12 months.CONCLUSIONS AND RELEVANCE: This study presents modeled estimates of the proportion of individuals with at least 1 of 3 self-reported Long COVID symptom clusters (persistent fatigue with bodily pain or mood swings; cognitive problems; or ongoing respiratory problems) 3 months after symptomatic SARS-CoV-2 infection.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng
700a Abbafati, Cristiana4 aut
700a Aerts, Joachim G4 aut
700a Al-Aly, Ziyad4 aut
700a Ashbaugh, Charlie4 aut
700a Ballouz, Tala4 aut
700a Blyuss, Oleg4 aut
700a Bobkova, Polina4 aut
700a Bonsel, Gouke4 aut
700a Borzakova, Svetlana4 aut
700a Buonsenso, Danilo4 aut
700a Butnaru, Denis4 aut
700a Carter, Austin4 aut
700a Chu, Helen4 aut
700a De Rose, Cristina4 aut
700a Diab, Mohamed Mustafa4 aut
700a Ekbom, Emil4 aut
700a El Tantawi, Maha4 aut
700a Fomin, Victor4 aut
700a Frithiof, Robertu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)robfr118
700a Gamirova, Aysylu4 aut
700a Glybochko, Petr V4 aut
700a Haagsma, Juanita A4 aut
700a Haghjooy Javanmard, Shaghayegh4 aut
700a Hamilton, Erin B4 aut
700a Harris, Gabrielle4 aut
700a Heijenbrok-Kal, Majanka H4 aut
700a Helbok, Raimund4 aut
700a Hellemons, Merel E4 aut
700a Hillus, David4 aut
700a Huijts, Susanne M4 aut
700a Hultström, Michael,d 1978-u Uppsala universitet,Anestesiologi och intensivvård,Institutionen för medicinsk cellbiologi4 aut0 (Swepub:uu)mihul498
700a Jassat, Waasila4 aut
700a Kurth, Florian4 aut
700a Larsson, Ing-Marie,d 1963-u Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)ingla697
700a Lipcsey, Miklósu Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)milip123
700a Liu, Chelsea4 aut
700a Loflin, Callan D4 aut
700a Malinovschi, Andrei,d 1978-u Uppsala universitet,Klinisk fysiologi4 aut0 (Swepub:uu)anmal535
700a Mao, Wenhui4 aut
700a Mazankova, Lyudmila4 aut
700a McCulloch, Denise4 aut
700a Menges, Dominik4 aut
700a Mohammadifard, Noushin4 aut
700a Munblit, Daniel4 aut
700a Nekliudov, Nikita A4 aut
700a Ogbuoji, Osondu4 aut
700a Osmanov, Ismail M4 aut
700a Peñalvo, José L4 aut
700a Petersen, Maria Skaalum4 aut
700a Puhan, Milo A4 aut
700a Rahman, Mujibur4 aut
700a Rass, Verena4 aut
700a Reinig, Nickolas4 aut
700a Ribbers, Gerard M4 aut
700a Ricchiuto, Antonia4 aut
700a Rubertsson, Stenu Uppsala universitet,Hedenstiernalaboratoriet4 aut0 (Swepub:uu)stenrube
700a Samitova, Elmira4 aut
700a Sarrafzadegan, Nizal4 aut
700a Shikhaleva, Anastasia4 aut
700a Simpson, Kyle E4 aut
700a Sinatti, Dario4 aut
700a Soriano, Joan B4 aut
700a Spiridonova, Ekaterina4 aut
700a Steinbeis, Fridolin4 aut
700a Svistunov, Andrey A4 aut
700a Valentini, Piero4 aut
700a van de Water, Brittney J4 aut
700a van den Berg-Emons, Rita4 aut
700a Wallin, Ewau Uppsala universitet,Anestesiologi och intensivvård4 aut0 (Swepub:uu)ewawa635
700a Witzenrath, Martin4 aut
700a Wu, Yifan4 aut
700a Xu, Hanzhang4 aut
700a Zoller, Thomas4 aut
700a Adolph, Christopher4 aut
700a Albright, James4 aut
700a Amlag, Joanne O4 aut
700a Aravkin, Aleksandr Y4 aut
700a Bang-Jensen, Bree L4 aut
700a Bisignano, Catherine4 aut
700a Castellano, Rachel4 aut
700a Castro, Emma4 aut
700a Chakrabarti, Suman4 aut
700a Collins, James K4 aut
700a Dai, Xiaochen4 aut
700a Daoud, Farah4 aut
700a Dapper, Carolyn4 aut
700a Deen, Amanda4 aut
700a Duncan, Bruce B4 aut
700a Erickson, Megan4 aut
700a Ewald, Samuel B4 aut
700a Ferrari, Alize J4 aut
700a Flaxman, Abraham D4 aut
700a Fullman, Nancy4 aut
700a Gamkrelidze, Amiran4 aut
700a Giles, John R4 aut
700a Guo, Gaorui4 aut
700a Hay, Simon I4 aut
700a He, Jiawei4 aut
700a Helak, Monika4 aut
700a Hulland, Erin N4 aut
700a Kereselidze, Maia4 aut
700a Krohn, Kris J4 aut
700a Lazzar-Atwood, Alice4 aut
700a Lindstrom, Akiaja4 aut
700a Lozano, Rafael4 aut
700a Malta, Deborah Carvalho4 aut
700a Månsson, Johan4 aut
700a Mantilla Herrera, Ana M4 aut
700a Mokdad, Ali H4 aut
700a Monasta, Lorenzo4 aut
700a Nomura, Shuhei4 aut
700a Pasovic, Maja4 aut
700a Pigott, David M4 aut
700a Reiner, Robert C4 aut
700a Reinke, Grace4 aut
700a Ribeiro, Antonio Luiz P4 aut
700a Santomauro, Damian Francesco4 aut
700a Sholokhov, Aleksei4 aut
700a Spurlock, Emma Elizabeth4 aut
700a Walcott, Rebecca4 aut
700a Walker, Ally4 aut
700a Wiysonge, Charles Shey4 aut
700a Zheng, Peng4 aut
700a Bettger, Janet Prvu4 aut
700a Murray, Christopher J L4 aut
700a Vos, Theo4 aut
710a Uppsala universitetb Anestesiologi och intensivvård4 org
773t Journal of the American Medical Association (JAMA)d : American Medical Association (AMA)g 328:16, s. 1604-1615q 328:16<1604-1615x 0098-7484x 1538-3598
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-489776
8564 8u https://doi.org/10.1001/jama.2022.18931

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