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Gelatin nanofibers :
Gelatin nanofibers : Recent insights in synthesis, bio-medical applications and limitations
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- El-Seedi, Hesham (author)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap,Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang 212013, Peoples R China.;Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm 32512, Egypt.,Farmakognosi
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- Said, Noha S. (author)
- Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm 32512, Egypt.
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- Yosri, Nermeen (author)
- Beni Suef Univ, Res Inst Med & Aromat Plants RIMAP, Chem Dept Med & Aromat Plants, Bani Suwayf 62514, Egypt.;Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China.
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- Hawash, Hamada B. (author)
- Natl Inst Oceanog & Fisheries, Environm Div, NIOF, Cairo, Egypt.
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- El-Sherif, Dina M. (author)
- Natl Inst Oceanog & Fisheries, NIOF, Cairo, Egypt.
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- Abouzid, Mohamed (author)
- Poznan Univ Med Sci, Fac Pharm, Dept Phys Pharm & Pharmacokinet, Poznan, Poland.
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- Abdel-Daim, Mohamed M. (author)
- Batterjee Med Coll, Dept Pharmaceut Sci, Pharm Program, POB 6231, Jeddah 21442, Saudi Arabia.;Suez Canal Univ, Fac Vet Med, Pharmacol Dept, Ismailia 41522, Egypt.
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- Yaseen, Mohammed (author)
- Univ West Scotland, Sch Comp Engn & Phys Sci, Paisley PA1 2BE, Scotland.
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- Omar, Hany (author)
- Univ Sharjah, Res Inst Med & Hlth Sci, Sharjah 27272, U Arab Emirates.
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- Shou, Qiyang (author)
- Zhejiang Chinese Med Univ, Clin Med Coll 2, Hangzhou, Peoples R China.
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- Attia, Nour F. (author)
- Natl Inst Stand 136, Chem Div, Gas Anal & Fire Safety Lab, Giza 12211, Egypt.
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- Zou, Xiaobo (author)
- Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China.
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- Guo, Zhiming (author)
- Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China.
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- Khalifa, Shaden A. M. (author)
- Capio St Gorans Hosp, Psychiat & Psychol Dept, Sankt Goransplan 1, S-11219 Stockholm, Sweden.
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(creator_code:org_t)
- Elsevier, 2023
- 2023
- English.
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In: Heliyon. - : Elsevier. - 2405-8440. ; 9:5
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Abstract
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- The use of gelatin and gelatin-blend polymers as environmentally safe polymers to synthesis electrospun nanofibers, has caused a revolution in the biomedical field. The development of efficient nanofibers has played a significant role in drug delivery, and for use in advanced scaffolds in regenerative medicine. Gelatin is an exceptional biopolymer, which is highly versatile, despite variations in the processing technology. The electrospinning process is an efficient technique for the manufacture of gelatin electrospun nanofibers (GNFs), as it is simple, efficient, and cost-effective. GNFs have higher porosity with large surface area and biocompatibility, despite that there are some drawbacks. These drawbacks include rapid degradation, poor mechanical strength, and complete dissolution, which limits the use of gelatin electrospun nanofibers in this form for biomedicine. Thus, these fibers need to be cross-linked, in order to control its solubility. This modification caused an improvement in the biological properties of GNFs, which made them suitable candidates for various biomedical applications, such as wound healing, drug delivery, bone regeneration, tubular scaffolding, skin, nerve, kidney, and cardiac tissue engineering. In this review an outline of electrospinning is shown with critical summary of literature evaluated with respect to the various applications of nanofibers-derived gelatin.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Biomaterial (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Bio Materials (hsv//eng)
Keyword
- Gelatin
- Electrospinning
- Nanofibers
- Medical application
- Tissue engineering
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- By the author/editor
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El-Seedi, Hesham
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Said, Noha S.
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Yosri, Nermeen
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Hawash, Hamada B ...
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El-Sherif, Dina ...
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Abouzid, Mohamed
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Abdel-Daim, Moha ...
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Yaseen, Mohammed
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Omar, Hany
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Shou, Qiyang
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Attia, Nour F.
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Zou, Xiaobo
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Guo, Zhiming
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Khalifa, Shaden ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Industrial Biote ...
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and Bio Materials
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Uppsala University