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One-year outcomes a...
One-year outcomes after transcatheter aortic valve implantation with the latest-generation SAPIEN balloonexpandable valve : the S3U registry
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- Cannata, Stefano (author)
- IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
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- Gandolfo, Caterina (author)
- IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
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- Ribichini, Flavio (author)
- Univ Verona, Div Cardiol, Dept Med, Verona, Italy.
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- Van Mieghem, Nicolas (author)
- Erasmus Univ, Dept Cardiol, Ctr Thorax, Med Ctr, Rotterdam, Netherlands.
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- Buccheri, Sergio (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Institutionen för medicinska vetenskaper
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- Barbanti, Marco (author)
- AOU Policlin G Rodolico San Marco, Div Cardiol, Catania, Italy.
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- Berti, Sergio (author)
- Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
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- Teles, Rui Campante (author)
- Hosp Santa Cruz, Nova Med Sch, CHLO, CEDOC, Lisbon, Portugal.
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- Bartorelli, Antonio L. (author)
- Univ Milan, Ctr Cardiol Monzino IRCCS, Milan, Italy.
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- Musumeci, Giuseppe (author)
- Mauriziano Hosp, Dept Cardiol, Turin, Italy.
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- Piva, Tommaso (author)
- Osped Riuniti Ancona, Intervent Cardiol, Ancona, Italy.
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- Nombela-Franco, Luis (author)
- Hosp Clin San Carlos, Cardiovasc Inst, Inst Invest Sanitaria San Carlos, Madrid, Spain.
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- La Spina, Ketty (author)
- IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy.
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- Palmerini, Tullio (author)
- IRCCS Univ Hosp Bologna, Cardio Thorac Vasc Dept, Cardiol Unit, Policlin S Orsola, Bologna, Italy.
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- Adrichem, Rik (author)
- Erasmus Univ, Dept Cardiol, Ctr Thorax, Med Ctr, Rotterdam, Netherlands.;Uppsala Univ Hosp, Dept Med Sci, Uppsala, Sweden.
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- Esposito, Augusto (author)
- Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
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- Lopes, Pedro (author)
- Hosp Santa Cruz, Nova Med Sch, CHLO, CEDOC, Lisbon, Portugal.
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- Olivares, Paolo (author)
- Univ Milan, Ctr Cardiol Monzino IRCCS, Milan, Italy.
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- Annibali, Gianmarco (author)
- Mauriziano Hosp, Dept Cardiol, Turin, Italy.
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- Nicolini, Elisa (author)
- Osped Riuniti Ancona, Intervent Cardiol, Ancona, Italy.
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- Marroquin, Luis (author)
- Hosp Clin San Carlos, Cardiovasc Inst, Inst Invest Sanitaria San Carlos, Madrid, Spain.
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- Tamburino, Corrado (author)
- Fdn CNR Reg Toscana G Monasterio, UOC Cardiol Diagnost & Interventist, Massa, Italy.
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- Tarantini, Giuseppe (author)
- Univ Padua, Dept Cardiac Thorac Vasc Sci & Publ Hlth, Intervent Cardiol Unit, Padua, Italy.
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- Saia, Francesco (author)
- IRCCS Univ Hosp Bologna, Cardio Thorac Vasc Dept, Cardiol Unit, Policlin S Orsola, Bologna, Italy.
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IRCCS, Dept Cardiothorac Surg, Unit Intervent Cardiol, UPMC,ISMETT,Mediterranean Inst Transplantat & Adv, Palermo, Italy Univ Verona, Div Cardiol, Dept Med, Verona, Italy. (creator_code:org_t)
- Europa Digital & Publishing, 2023
- 2023
- English.
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In: EuroIntervention. - : Europa Digital & Publishing. - 1774-024X .- 1969-6213. ; 18:17, s. 1418-
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
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- Background: Initial data about the performance of the new-generation SAPIEN 3 Ultra (S3U) valve are highly promising. However, evidence about the longer-term performance and safety of the S3U is scarce.Aims: We aimed to investigate the 1-year clinical and echocardiographic outcomes of transcatheter aortic valve implantation (TAVI) using the S3U compared with its predecessor, the SAPIEN 3 valve (S3).Methods: The SAPIEN 3 Ultra registry included consecutive patients who underwent transfemoral TAVI at 12 European centres with the S3U or S3 between October 2016 and December 2020. One-to-one propensity score (PS) matching was performed to account for differences in baseline characteristics. The primary outcomes of interest were all-cause death and the composite of all-cause death, disabling stroke and hospitalisation for heart failure at 1 year.Results: The overall study cohort encompassed 1,692 patients treated with either the S3U (n=519) or S3 (n=1,173). The PS-matched population had a total of 992 patients (496 per group). At 1 year, the rate of death from any cause was 4.9% in the S3U group and 6.3% in the S3 group (p=0.743). Similarly, there were no significant differences in the rates of the primary composite outcome (9.5% in the S3 group and 6.6% in the S3U group; p=0.162). The S3U was associated with lower rates of mild paravalvular leak (PVL) compared with the S3 (odds ratio 0.63, 95% confidence interval: 0.44 to 0.88; p<0.01). No significant differences in transprosthetic gradients were observed between the two groups.Conclusions: Compared with the S3, the S3U transcatheter heart valve was associated with similar 1-year clinical outcomes but reduced rates of mild PVL.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- femoral
- miscellaneous
- paravalvular leak
- TAVI
- transthoracic echocardiogram
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Cannata, Stefano
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Gandolfo, Cateri ...
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Ribichini, Flavi ...
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Van Mieghem, Nic ...
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Buccheri, Sergio
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Barbanti, Marco
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Berti, Sergio
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Teles, Rui Campa ...
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Bartorelli, Anto ...
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Musumeci, Giusep ...
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Piva, Tommaso
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Nombela-Franco, ...
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La Spina, Ketty
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Palmerini, Tulli ...
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Adrichem, Rik
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Esposito, August ...
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Lopes, Pedro
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Olivares, Paolo
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Annibali, Gianma ...
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Nicolini, Elisa
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Marroquin, Luis
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Tamburino, Corra ...
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Tarantini, Giuse ...
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Saia, Francesco
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
- Articles in the publication
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EuroIntervention
- By the university
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Uppsala University