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Search: onr:"swepub:oai:DiVA.org:uu-512601" > Investigating the d...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005067naa a2200469 4500
001oai:DiVA.org:uu-512601
003SwePub
008230927s2023 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5126012 URI
0247 a https://doi.org/10.1007/s00702-023-02616-72 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a de Vries, Lyssau Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut
2451 0a Investigating the development of the autonomic nervous system in infancy through pupillometry
264 c 2023-03-12
264 1b Springer,c 2023
338 a print2 rdacarrier
520 a We aim to investigate early developmental trajectories of the autonomic nervous system (ANS) as indexed by the pupillary light reflex (PLR) in infants with (i.e. preterm birth, feeding difficulties, or siblings of children with autism spectrum disorder) and without (controls) increased likelihood for atypical ANS development. We used eye-tracking to capture the PLR in 216 infants in a longitudinal follow-up study spanning 5 to 24 months of age, and linear mixed models to investigate effects of age and group on three PLR parameters: baseline pupil diameter, latency to constriction and relative constriction amplitude. An increase with age was found in baseline pupil diameter (F(3,273.21) = 13.15, p < 0.001, eta(2)(p) = 0.13), latency to constriction (F(3,326.41) =3.84, p = 0.010,eta(2)(p) = 0.03) and relative constriction amplitude(F(3,282.53) =3.70, p = 0.012,eta(2)(p)= 0.04). Group differences were found for baseline pupil diameter (F(3,235.91) = 9.40, p < 0.001,eta(2)(p) = 0.11), with larger diameter in preterms and siblings than in controls, and for latency to constriction (F(3,237.10) = 3.48, p = 0.017, eta(2)(p) = 0.04), with preterms having a longer latency than controls. The results align with previous evidence, with development over time that could be explained by ANS maturation. To better understand the cause of the group differences, further research in a larger sample is necessary, combining pupillometry with other measures to further validate its value.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng
653 a Pupillometry
653 a Infant development
653 a Autonomic nervous system
653 a Autism spectrum disorder
653 a Preterm birth
7001 a Amelynck, Steffieu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut
7001 a Nyström, Pär,d 1975-u Uppsala universitet,Institutionen för psykologi4 aut0 (Swepub:uu)panys031
7001 a van Esch, Lotteu Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.4 aut
7001 a Van Lierde, Thijsu Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut
7001 a Warreyn, Petrau Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut
7001 a Roeyers, Herbertu Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.4 aut
7001 a Noens, Ilseu Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.4 aut
7001 a Naulaers, Gunnaru Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Dept Dev & Regenerat, Woman & Child, Louvain, Belgium.4 aut
7001 a Boets, Bartu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut
7001 a Steyaert, Jeanu Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 aut
7102 a Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.b Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.4 org
7730 t Journal of neural transmissiond : Springerg 130, s. 723-734q 130<723-734x 0300-9564x 1435-1463
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-512601
8564 8u https://doi.org/10.1007/s00702-023-02616-7

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