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Investigating the d...
Investigating the development of the autonomic nervous system in infancy through pupillometry
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- de Vries, Lyssa (author)
- Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.
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- Amelynck, Steffie (author)
- Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.
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- Nyström, Pär, 1975- (author)
- Uppsala universitet,Institutionen för psykologi
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- van Esch, Lotte (author)
- Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.
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- Van Lierde, Thijs (author)
- Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.
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- Warreyn, Petra (author)
- Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.
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- Roeyers, Herbert (author)
- Univ Ghent, Dept Expt Clin & Hlth Psychol, RIDDL Lab, Ghent, Belgium.
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- Noens, Ilse (author)
- Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.;Katholieke Univ Leuven, Fac Psychol & Educ Sci, Parenting & Special Educ Res Unit, Louvain, Belgium.
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- Naulaers, Gunnar (author)
- Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Dept Dev & Regenerat, Woman & Child, Louvain, Belgium.
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- Boets, Bart (author)
- Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.
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- Steyaert, Jean (author)
- Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium.
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Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium;Univ Hosp Leuven, Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium. Katholieke Univ Leuven, Ctr Dev Psychiat, Dept Neurosci, Herestr 49,Box 1029, B-3000 Louvain, Belgium.;Katholieke Univ Leuven, Leuven Autism Res LAuRes, Louvain, Belgium. (creator_code:org_t)
- 2023-03-12
- 2023
- English.
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In: Journal of neural transmission. - : Springer. - 0300-9564 .- 1435-1463. ; 130, s. 723-734
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- We aim to investigate early developmental trajectories of the autonomic nervous system (ANS) as indexed by the pupillary light reflex (PLR) in infants with (i.e. preterm birth, feeding difficulties, or siblings of children with autism spectrum disorder) and without (controls) increased likelihood for atypical ANS development. We used eye-tracking to capture the PLR in 216 infants in a longitudinal follow-up study spanning 5 to 24 months of age, and linear mixed models to investigate effects of age and group on three PLR parameters: baseline pupil diameter, latency to constriction and relative constriction amplitude. An increase with age was found in baseline pupil diameter (F(3,273.21) = 13.15, p < 0.001, eta(2)(p) = 0.13), latency to constriction (F(3,326.41) =3.84, p = 0.010,eta(2)(p) = 0.03) and relative constriction amplitude(F(3,282.53) =3.70, p = 0.012,eta(2)(p)= 0.04). Group differences were found for baseline pupil diameter (F(3,235.91) = 9.40, p < 0.001,eta(2)(p) = 0.11), with larger diameter in preterms and siblings than in controls, and for latency to constriction (F(3,237.10) = 3.48, p = 0.017, eta(2)(p) = 0.04), with preterms having a longer latency than controls. The results align with previous evidence, with development over time that could be explained by ANS maturation. To better understand the cause of the group differences, further research in a larger sample is necessary, combining pupillometry with other measures to further validate its value.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Pupillometry
- Infant development
- Autonomic nervous system
- Autism spectrum disorder
- Preterm birth
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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de Vries, Lyssa
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Amelynck, Steffi ...
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Nyström, Pär, 19 ...
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van Esch, Lotte
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Van Lierde, Thij ...
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Warreyn, Petra
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Roeyers, Herbert
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Noens, Ilse
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Naulaers, Gunnar
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Boets, Bart
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Steyaert, Jean
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
- Articles in the publication
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Journal of neura ...
- By the university
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Uppsala University