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HEART-score can be simplified without loss of discriminatory power in patients with chest pain : Introducing the HET-score

Löfmark, Henrik (author)
Karolinska Inst, Danderyd Univ Hosp, Dept Clin Sci, Stockholm, Sweden.;Karolinska Inst, Danderyds Univ Hosp, Dept Clin Sci, Dept Cardiol, S-18288 Stockholm, Sweden.
Muhrbeck, Josephine (author)
Karolinska Inst, Danderyd Univ Hosp, Dept Clin Sci, Stockholm, Sweden.
Eggers, Kai M., 1962- (author)
Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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Linder, Rickard (author)
Karolinska Inst, Danderyd Univ Hosp, Dept Clin Sci, Stockholm, Sweden.
Ljung, Lina (author)
Karolinska Inst, Dept Clin Sci, Sodersjukhuset, Stockholm, Sweden.
Martinsson, Arne (author)
Capio St Gorans Hosp, Stockholm, Sweden.
Melki, Dina (author)
Ersta Hosp, Dept Med, Stockholm, Sweden.
Sarkar, Nondita (author)
Karolinska Institutet
Svensson, Per (author)
Karolinska Institutet
Lindahl, Bertil, 1957- (author)
Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
Jernberg, Tomas (author)
Karolinska Institutet
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Karolinska Inst, Danderyd Univ Hosp, Dept Clin Sci, Stockholm, Sweden;Karolinska Inst, Danderyds Univ Hosp, Dept Clin Sci, Dept Cardiol, S-18288 Stockholm, Sweden. Karolinska Inst, Danderyd Univ Hosp, Dept Clin Sci, Stockholm, Sweden. (creator_code:org_t)
Elsevier, 2023
2023
English.
In: American Journal of Emergency Medicine. - : Elsevier. - 0735-6757 .- 1532-8171. ; 74, s. 104-111
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • BackgroundThe History, Electrocardiogram (ECG), Age, Risk factors and Troponin, (HEART) score is useful for early risk stratification in chest pain patients. The aim was to validate previous findings that a simplified score using history, ECG and troponin (HET-score) has similar ability to stratify risk.MethodsPatients presenting with chest pain with duration of ≥10 min and an onset of last episode ≤12 h but without ST-segment elevation on ECG at 6 emergency departments were eligible for inclusion. The HEART-score and the simplified HET-score were calculated. The endpoint was a composite of myocardial infarction (MI) as index diagnosis, readmission due to new MI or death within 30 days.ResultsHEART-score identified 32% as low risk (0-2p), 47% as intermediate risk (3-5p), and 20% as high risk (6-10p) patients. The endpoint occurred in 0.5%, 7.3% and 35.7%, respectively. HET-score identified 39%, 42% and 19% as low- (0p), intermediate- (1-2p) and high-risk (3-6p) patients, with the endpoint occurring in 0.6%, 6.2% and 43.2%, respectively.When all variables included in the HEART-score were included in a multivariable logistic regression analysis, only History (OR, CI [95%]): 2.97(2.16–4.09), ECG (1.61[1.14–2.28]) and troponin level (5.21[3.91–6.95]) were significantly associated with cardiovascular events. When HEART- and HET-score were compared in a ROC-analysis, HET-score had a significantly larger AUC (0.887 vs 0.853, p < 0.001).ConclusionsCompared with HEART-score, HET-score is simpler and appears to have similar ability to discriminate between chest pain patients with and without cardiovascular event.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

Chest pain
Acute coronary syndrome
Score
Diagnosis
Prognosis

Publication and Content Type

ref (subject category)
art (subject category)

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