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Associations of hea...
Associations of health-related quality of life with major adverse cardiovascular and cerebrovascular events for individuals with ischaemic heart disease : systematic review, meta-analysis and evidence mapping
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- Soloveva, Anzhela (author)
- Almazov Natl Med Res Ctr, Dept Cardiol, St Petersburg, Russia.
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- Gale, Chris P. (author)
- Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Data Analyt, Leeds, England.
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- Tun, Han Naung (author)
- Univ Vermont, Larner Coll Med, Burlington, VT USA.
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- Hurdus, Ben (author)
- Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Data Analyt, Leeds, England.
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- Aktaa, Suleman (author)
- Leeds Gen Infirm, Dept Cardiol, Leeds, England.
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- Palin, Victoria (author)
- Leeds Gen Infirm, Dept Cardiol, Leeds, England.
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- Mebrahtu, Teumzghi F. (author)
- Bradford Teaching Hosp NHS Fdn Trust, Bradford Inst Hlth Res, Bradford, England.
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- Van Spall, Harriette (author)
- Populat Hlth Res Inst, Hamilton, ON, Canada.;McMaster Univ, Div Cardiol, Hamilton, ON, Canada.
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- Batra, Gorav (author)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala Univ, Sweden; Uppsala Univ, Sweden
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- Dondo, Tatendashe Bernadette (author)
- Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Data Analyt, Leeds, England.
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- Bäck, Maria (author)
- Linköpings universitet,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten
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- Munyombwe, Theresa (author)
- Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Data Analyt, Leeds, England.
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Almazov Natl Med Res Ctr, Dept Cardiol, St Petersburg, Russia Univ Leeds, Leeds Inst Cardiovasc & Metab Med, Leeds Inst Data Analyt, Leeds, England. (creator_code:org_t)
- BMJ Publishing Group Ltd, 2023
- 2023
- English.
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In: Open heart. - : BMJ Publishing Group Ltd. - 2053-3624. ; 10:2
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Abstract
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- Objective To investigate the association between health-related quality of life (HRQoL) and major adverse cardiovascular and cerebrovascular events (MACCE) in individuals with ischaemic heart disease (IHD).Methods Medline(R), Embase, APA PsycINFO and CINAHL (EBSCO) from inception to 3 April 2023 were searched. Studies reporting association of HRQoL, using a generic or cardiac-specific tool, with MACCE or components of MACCE for individuals with IHD were eligible for inclusion. Risk of bias was assessed using the Newcastle-Ottawa Quality Assessment Scale to assess the quality of the studies. Descriptive synthesis, evidence mapping and random-effects meta-analysis were performed stratified by HRQoL measures and effect estimates. Between-study heterogeneity was assessed using the Higgins I2 statistic.Results Fifty-one articles were included with a total of 134 740 participants from 53 countries. Meta-analysis of 23 studies found that the risk of MACCE increased with lower baseline HeartQoL score (HR 1.49, 95% CI 1.16 to 1.93) and Short Form Survey (SF-12) physical component score (PCS) (HR 1.39, 95% CI 1.28 to 1.51). Risk of all-cause mortality increased with a lower HeartQoL (HR 1.64, 95% CI 1.34 to 2.01), EuroQol 5-dimension (HR 1.17, 95% CI 1.12 to 1.22), SF-36 PCS (HR 1.29, 95% CI 1.19 to 1.41), SF-36 mental component score (HR 1.18, 95% CI 1.08 to 1.30).Conclusions This study found an inverse association between baseline values or change in HRQoL and MACCE or components of MACCE in individuals with IHD, albeit with between-study heterogeneity. Standardisation and routine assessment of HRQoL in clinical practice may help risk stratify individuals with IHD for tailored interventions.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Keyword
- health-related quality of life
- cardiovascular outcomes
- mortality
- systematic review
- meta-analysis
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Open heart
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- By the author/editor
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Soloveva, Anzhel ...
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Gale, Chris P.
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Tun, Han Naung
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Hurdus, Ben
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Aktaa, Suleman
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Palin, Victoria
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Mebrahtu, Teumzg ...
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Van Spall, Harri ...
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Batra, Gorav
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Dondo, Tatendash ...
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Bäck, Maria
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Munyombwe, There ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cardiac and Card ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nursing
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Open heart
- By the university
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Uppsala University
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Linköping University