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Scandiatransplant E...
Scandiatransplant Exchange Program (STEP) : Development and Results From an International Kidney Exchange Program
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- Weinreich, Ilse Duus (author)
- Scandiatransplant Off, Aarhus, Denmark.
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- Andersson, Tommy (author)
- Lund University,Lunds universitet,Nationalekonomiska institutionen,Ekonomihögskolan,Department of Economics,Lund University School of Economics and Management, LUSEM
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- Andresdottir, Margret Birna (author)
- Landspitali Univ Hosp, Dept Nephrol, Reykjavik, Iceland.
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- Bengtsson, Mats (author)
- Uppsala universitet,Institutionen för immunologi, genetik och patologi
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- Biglarnia, Alireza (author)
- Skane Univ Hosp, Dept Nephrol, Malmö, Sweden.
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- Bistrup, Claus (author)
- Odense Univ Hosp, Dept Nephrol, Odense, Denmark.,Odense University Hospital
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- Boulland, Line (author)
- Oslo Univ Hosp, Dept Immunol & Transfus Med, Oslo, Norway.
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- Bruunsgaard, Helle (author)
- Copenhagen Univ Hosp, Rigshosp, Dept Clin Immunol, Copenhagen, Denmark.,Copenhagen University Hospital
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- Helantera, Ilkka (author)
- Helsinki Univ Hosp, Transplantat & Liver Surg, Helsinki, Finland.
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- Kolvald, Kulli (author)
- Tartu Univ Hosp, Dept Nephrol, Tartu, Estonia.
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- Lauronen, Jouni (author)
- Finnish Red Cross Blood Serv, Helsinki, Finland.
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- Lindahl, Jorn Petter (author)
- Oslo Univ Hosp, Dept Transplant Med, Oslo, Norway.
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- Skov, Karin (author)
- Aarhus Univ Hosp, Dept Renal Med, Aarhus, Denmark.,Aarhus University Hospital
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- Schwarz Sorensen, Soren (author)
- Copenhagen Univ Hosp, Rigshosp, Dept Nephrol, Copenhagen, Denmark.,Copenhagen University Hospital
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- Wennberg, Lars (author)
- Karolinska Institutet,Karolinska University Hospital
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- Lindner, Per (author)
- Univ Gothenburg, Inst Clin Sci, Sahlgrenska Acad, Transplantat Ctr, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Transplantat Ctr, S-41345 Gothenburg, Sweden.,Sahlgrenska University Hospital,Sahlgrenska Academy
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- Biglarnia, Ali Reza (author)
- Skåne University Hospital
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Boulland, Jean-Luc (author)
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Scandiatransplant Off, Aarhus, Denmark Nationalekonomiska institutionen (creator_code:org_t)
- Lippincott Williams & Wilkins, 2023
- 2023
- English.
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In: Transplantation direct. - : Lippincott Williams & Wilkins. - 2373-8731. ; 9:11
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Abstract
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- Background. Kidney transplant candidates may be incompatible with their intended living donors because of the presence of antibodies against HLA and/or ABO. To increase the possibility of finding an acceptable kidney donor for these patients, the Scandiatransplant Exchange Program (STEP) program within Scandiatransplant was launched in 2019.Methods. This is a retrospective review of our experiences from the first 4 y of the STEP program, including details about the match runs, performed transplantations, and recipient outcomes within the program.Results. During 2019-2022, 11 match runs and 4 reruns were performed. In total, 114 pairs and 6 anonymous donors participated in these match runs. Fifty-one pairs (45%) participated in 1 match run, 31 pairs (27%) participated in 2 match runs, and 32 pairs (29%) participated in >= 3 match runs. Seventy-two individuals (63%) participated because of HLA incompatibility, 19 (17%) because of ABO incompatibility, and 7 (6%) because of both HLA and ABO incompatibility. Forty percent of the patients enrolled in the program underwent transplantation. In total, 49 transplantations have so far been performed within the program, and 46 (94%) of the recipients had a functioning kidney graft at follow-up in February 2023.Results. During 2019-2022, 11 match runs and 4 reruns were performed. In total, 114 pairs and 6 anonymous donors participated in these match runs. Fifty-one pairs (45%) participated in 1 match run, 31 pairs (27%) participated in 2 match runs, and 32 pairs (29%) participated in >= 3 match runs. Seventy-two individuals (63%) participated because of HLA incompatibility, 19 (17%) because of ABO incompatibility, and 7 (6%) because of both HLA and ABO incompatibility. Forty percent of the patients enrolled in the program underwent transplantation. In total, 49 transplantations have so far been performed within the program, and 46 (94%) of the recipients had a functioning kidney graft at follow-up in February 2023.Conclusions. The STEP program offers sensitized patients an enlarged pool of living donors and a chance of a compatible international living donor, resulting in an increased number of total transplantations. Currently, STEP is one of the largest transnational kidney exchange programs and has improved the situation for patients waiting for kidney transplantation in Scandiatransplant.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- SAMHÄLLSVETENSKAP -- Ekonomi och näringsliv -- Nationalekonomi (hsv//swe)
- SOCIAL SCIENCES -- Economics and Business -- Economics (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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Weinreich, Ilse ...
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Andersson, Tommy
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Andresdottir, Ma ...
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Bengtsson, Mats
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Biglarnia, Alire ...
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Bistrup, Claus
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Boulland, Line
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Bruunsgaard, Hel ...
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Helantera, Ilkka
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Kolvald, Kulli
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Lauronen, Jouni
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Lindahl, Jorn Pe ...
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Skov, Karin
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Schwarz Sorensen ...
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Wennberg, Lars
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Lindner, Per
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Biglarnia, Ali R ...
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Boulland, Jean-L ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- SOCIAL SCIENCES
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SOCIAL SCIENCES
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and Economics and Bu ...
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and Economics
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Transplantation ...
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Uppsala University
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Lund University