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Associations betwee...
Associations between maternal overweight/obesity during pregnancy and body composition in young adult offspring
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- Rerkasem, Amaraporn (author)
- Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand.
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- Lyons-Reid, Jaz (author)
- Univ Auckland, Liggins Inst, Auckland, New Zealand.
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- Namwongprom, Sirianong (author)
- Chiang Mai Univ, Fac Med, Dept Radiol, Chiang Mai, Thailand.
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- Wongsrithep, Suthathip (author)
- Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand.
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- Mangklabruks, Ampica (author)
- Chiang Mai Univ, Fac Med, Dept Internal Med, Chiang Mai, Thailand.
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- Phirom, Kochaphan (author)
- Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand.
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- Rerkasem, Kittipan (author)
- Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand.;Chiang Mai Univ, Fac Med, Clin Surg Res Ctr, Dept Surg, Chiang Mai, Thailand.
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- Derraik, José G. B. (author)
- Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning,Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand.;Univ Auckland, Fac Med & Hlth Sci, Dept Paediat Child & Youth Hlth, Auckland, New Zealand.
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Chiang Mai Univ, Res Inst Hlth Sci, Environm Occupat Hlth Sci & Noncommunicable Dis Re, Chiang Mai, Thailand Univ Auckland, Liggins Inst, Auckland, New Zealand. (creator_code:org_t)
- Frontiers Media S.A. 2024
- 2024
- English.
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In: Frontiers in Public Health. - : Frontiers Media S.A.. - 2296-2565. ; 12
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https://uu.diva-port... (primary) (Raw object)
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Abstract
Subject headings
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- Background: Maternal obesity is associated with an increased risk of large-for-gestational-age births and childhood obesity. However, evidence on its potential associations with long-term offspring body composition remains limited. This prospective cohort study examined associations between maternal body mass index (BMI) during pregnancy and body composition in the young adult offspring.Methods: Participants were the offspring from a birth cohort in Chiang Mai (Thailand). Maternal BMI was assessed at the first antenatal clinic visit (≤ 24 weeks of gestation) in 1989-1990. In 2010-2011, we followed up the offspring at approximately 20 years of age, assessing their body composition using whole-body dual-energy X-ray absorptiometry (DXA) scans. Associations between maternal BMI and offspring body composition were explored using unadjusted and adjusted analyses.Results: We assessed 391 young adults (55% were females). Higher maternal BMI was associated with increased offspring fat mass and lean mass. In adjusted analyses, offspring of mothers with overweight/obesity exhibited total body fat percentages 1.5 (95% CI 0.1, 2.9; p = 0.032) and 2.3 (95% CI 0.2, 4.5; p = 0.036) percentage points higher than offspring of normal-weight and underweight mothers, respectively. Fat mass index was similarly higher: 0.9 kg/m2 (95% CI 0.3, 1.5 kg/m2; p = 0.002) and 1.4 kg/m2 (95% CI 0.5, 2.3 kg/m2; p = 0.002), respectively. However, no differences in visceral adiposity were detected.Conclusion: Higher maternal BMI during pregnancy was associated with increased adiposity in young adult offspring. Our findings suggest that the cross-generational transmission of maternal obesity-related traits is associated with increased offspring adiposity in the long term.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- adiposity
- birth cohort
- body fat
- dual-energy X-ray absorptiometry
- DXA
- follow-up
Publication and Content Type
- ref (subject category)
- art (subject category)
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