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Studies in children...
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Ciba, IrisUppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Uppsala Univ, Childrens Hosp, Uppsala, Sweden.
(author)
Studies in children with obesity in two European treatment centres show a high prevalence of impaired glucose metabolism in the Swedish cohort
- Article/chapterEnglish2024
Publisher, publication year, extent ...
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John Wiley & Sons,2024
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Numbers
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LIBRIS-ID:oai:DiVA.org:uu-528162
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-528162URI
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https://doi.org/10.1111/apa.17030DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Aim: To investigate the prevalence and possible risk factors for the development of impaired glucose metabolism in children and adolescents with obesity.Methods: This was a cross-sectional retrospective cohort study, including 634 patients with obesity and 98 normal weight controls aged 4-18 years from the Beta-cell function in Juvenile Diabetes and Obesity (Beta-JUDO) cohort, a dual-centre study at Uppsala University Hospital (Sweden) and Paracelsus Medical University Hospital (Salzburg, Austria) conducted between 2012 and 2021. A longitudinal subgroup analysis, including 188 of these subjects was performed. Impaired glucose metabolism was diagnosed by oral glucose tolerance tests according to American Diabetes Association criteria.Results: The prevalence of impaired glucose metabolism was 72% in Uppsala patients, 24% in Salzburg patients, 30% in Uppsala controls and 13% in Salzburg controls. The prevalence was lower at the follow-up visits compared with baseline both in Uppsala and Salzburg patients. A family history of type 2 diabetes showed the strongest association with impaired glucose metabolism at the follow-up visits besides belonging to the Uppsala cohort.Conclusion: The prevalence of impaired glucose metabolism was extraordinarily high in Swedish children and adolescents with obesity, but decreased during the follow-up period.
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Dahlbom, MarieUppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Uppsala Univ, Childrens Hosp, Uppsala, Sweden.(Swepub:uu)marda124
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Manell, HannesUppsala universitet,Institutionen för medicinsk cellbiologi,Uppsala Univ, Childrens Hosp, Uppsala, Sweden.(Swepub:uu)hanoh982
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Mörwald, KatharinaParacelsus Med Univ, Dept Pediat, Salzburg, Austria.;Paracelsus Med Univ, Obes Res Unit, Salzburg, Austria.
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Roomp, KirstenUniv Luxembourg, Luxembourg Ctr Syst Biomed, Belvaux, Luxembourg.
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Weghuber, DanielParacelsus Med Univ, Dept Pediat, Salzburg, Austria.;Paracelsus Med Univ, Obes Res Unit, Salzburg, Austria.
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Bergsten, PeterUppsala universitet,Institutionen för medicinsk cellbiologi,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Uppsala Univ, Childrens Hosp, Uppsala, Sweden.(Swepub:uu)peteberg
(author)
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Forslund, Anders,1961-Uppsala universitet,Pediatrisk inflammations- och metabolismforskning samt barnhälsa,Uppsala Univ, Childrens Hosp, Uppsala, Sweden.(Swepub:uu)andeforsl
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Uppsala universitetPediatrisk inflammations- och metabolismforskning samt barnhälsa
(creator_code:org_t)
Related titles
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In:Acta Paediatrica: John Wiley & Sons113:2, s. 286-2950803-52531651-2227
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