Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways

Basile, Giorgio (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Vetere, Amedeo (author)

Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

Hu, Jiang (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

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Ijaduola, Oluwaseun (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Zhang, Yi (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Liu, Ka‐Cheuk (author)

Karolinska Institutet,Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

Eltony, Amira M. (author)

Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA.

De Jesus, Dario F. (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Fukuda, Kazuki (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Doherty, Grace (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

Leech, Colin A. (author)

Department of Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA.

Chepurny, Oleg G. (author)

Department of Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA.

Holz, George G. (author)

Department of Medicine, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA; Department of Pharmacology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY 13210, USA.

Yun, Seok-Hyun (author)

Harvard Medical School and Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA.

Andersson, Olov (author)

Karolinska Institutet,Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

Choudhary, Amit (author)

Wagner, Bridget K. (author)

Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

Kulkarni, Rohit N. (author)

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA.

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Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA 02215, USA Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. (creator_code:org_t)

2023

2023

English.

In: Cell Metabolism. - 1550-4131 .- 1932-7420. ; 35:7, s. 1242-1260.e9

Related links:

https://urn.kb.se/re...

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https://doi.org/10.1...

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• Journal article (peer-reviewed)