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Single-session visu...
Single-session visuospatial task procedure to prevent childbirth-related posttraumatic stress disorder : a multicentre double-blind randomised controlled trial
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- Deforges, Camille (author)
- Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland.
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- Sandoz, Vania (author)
- Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland.;Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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- Noël, Yvonnick (author)
- Rennes 2 Univ, Dept Psychol, Rennes, France.
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- Avignon, Valérie (author)
- Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland.;Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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- Desseauve, David (author)
- Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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- Bourdin, Julie (author)
- Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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- Vial, Yvan (author)
- Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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- Ayers, Susan (author)
- City Univ London, Ctr Maternal & Child Hlth Res, London, England.
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- Holmes, Emily A. (author)
- Uppsala universitet,Institutionen för psykologi
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- Epiney, Manuella (author)
- Geneva Univ Hosp, Dept Woman Child & Teenager, Geneva, Switzerland.
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- Horsch, Antje (author)
- Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland.;Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland.
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Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland Univ Lausanne, Inst Higher Educ & Res Healthcare, Lausanne, Vaud, Switzerland.;Lausanne Univ Hosp, Dept Woman Mother Child, Lausanne, Vaud, Switzerland. (creator_code:org_t)
- Springer Nature, 2023
- 2023
- English.
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In: Molecular Psychiatry. - : Springer Nature. - 1359-4184 .- 1476-5578. ; 28:9, s. 3842-3850
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https://uu.diva-port... (primary) (Raw object)
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Abstract
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- Preventive evidence-based interventions for childbirth-related posttraumatic stress disorder (CB-PTSD) are lacking. Yet, 18.5% of women develop CB-PTSD symptoms following an unplanned caesarean section (UCS). This two-arm, multicentre, double-blind superiority trial tested the efficacy of an early single-session intervention including a visuospatial task on the prevention of maternal CB-PTSD symptoms. The intervention was delivered by trained maternity clinicians. Shortly after UCS, women were included if they gave birth to a live baby, provided consent, and perceived their childbirth as traumatic. Participants were randomly assigned to the intervention or attention-placebo group (allocation ratio 1:1). Assessments were done at birth, six weeks, and six months postpartum. Group differences in maternal CB-PTSD symptoms at six weeks (primary outcomes) and six months postpartum (secondary outcomes) were assessed with the self-report PTSD Checklist for DSM-5 (PCL-5) and by blinded research assessors with the Clinician-administered PTSD scale for DSM-5 (CAPS-5). Analysis was by intention-to-treat. The trial was prospectively registered (ClinicalTrials.gov, NCT03576586). Of the 2068 women assessed for eligibility, 166 were eligible and 146 were randomly assigned to the intervention (n = 74) or attention-placebo control group (n = 72). For the PCL-5, at six weeks, a marginally significant intervention effect was found on the total PCL-5 PTSD symptom count (β = −0.43, S.E. = 0.23, z = −1.88, p < 0.06), and on the intrusions (β = −0.73, S.E. = 0.38, z = −1.94, p < 0.0525) and arousal (β = −0.55, S.E. = 0.29, z = −1.92, p < 0.0552) clusters. At six months, a significant intervention effect on the total PCL-5 PTSD symptom count (β = −0.65, S.E. = 0.32, z = −2.04, p = 0.041, 95%CI[−1.27, −0.03]), on alterations in cognition and mood (β = −0.85, S.E. = 0.27, z = −3.15, p = 0.0016) and arousal (β = −0.56, S.E. = 0.26, z = −2.19, p < 0.0289, 95%CI[−1.07, −0.06]) clusters appeared. No group differences on the CAPS-5 emerged. Results provide evidence that this brief, single-session intervention carried out by trained clinicians can prevent the development of CB-PTSD symptoms up to six months postpartum.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Deforges, Camill ...
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Sandoz, Vania
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Noël, Yvonnick
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Avignon, Valérie
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Desseauve, David
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Bourdin, Julie
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show more...
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Vial, Yvan
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Ayers, Susan
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Holmes, Emily A.
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Epiney, Manuella
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Horsch, Antje
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Obstetrics Gynae ...
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Molecular Psychi ...
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Uppsala University