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Patterns of practice of image guided particle therapy for cranio-spinal irradiation : A site specific multi-institutional survey of European Particle Therapy Network

Trnková, Petra (author)
Dasu, Alexandru, 1972- (author)
Uppsala universitet,Institutionen för immunologi, genetik och patologi
Placidi, Lorenzo (author)
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Stock, Markus (author)
Toma-Dasu, Iuliana (author)
Brouwer, Charlotte L. (author)
Gosling, Andrew (author)
Jouglar, Emmanuel (author)
Kristensen, Ingrid (author)
Martin, Valentine (author)
Moinuddin, Syed (author)
Pasquie, Isabelle (author)
Peters, Sarah (author)
Pica, Alessia (author)
Plaude, Sandija (author)
Righetto, Roberto (author)
Rombi, Barbara (author)
Thariat, Juliette (author)
van der Weide, Hiske (author)
Hoffmann, Aswin (author)
Bolsi, Alessandra (author)
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 (creator_code:org_t)
Elsevier, 2024
2024
English.
In: Physica medica (Testo stampato). - : Elsevier. - 1120-1797 .- 1724-191X. ; 123
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • PurposeTo investigate the current practice patterns in image-guided particle therapy (IGPT) for cranio-spinal irradiation (CSI).MethodsA multi-institutional survey was distributed to European particle therapy centres to analyse all aspects of IGPT. Based on the survey results, a Delphi consensus analysis was developed to define minimum requirements and optimal workflow for clinical practice. The centres participating in the institutional survey were invited to join the Delphi process.ResultsEleven centres participated in the survey. Imaging for treatment planning was rather similar among the centres with Computed Tomography (CT) being the main modality. For positioning verification, 2D IGPT was more commonly used than 3D IGPT. Two centres performed routinely imaging for plan adaptation, by the rest ad hoc. Eight centres participated in the Delphi consensus analysis. The full consensus was reached on the use of CT imaging without contrast for treatment planning and the role of magnetic resonance imaging (MRI) in target and organs-at-risk delineation. There was an agreement on the necessity to perform patient position verification and correction before each isocentre. The most important outcome was the clear need for standardization and harmonization of the workflow.ConclusionThere were differences in CSI IGPT clinical practice among the European particle therapy centres. Moreover, the optimal workflow as identified by experts was not yet reached. There is a strong need for consensus guidelines. The state-of-the-art imaging technology and protocols need to be implemented into clinical practice to improve the quality of IGPT for CSI.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

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