Synthesis, biological evaluation, and modeling studies of inhibitors aimed at the malarial proteases plasmepsins I and II.

Keyword

Animals

Antimalarials/*chemical synthesis/chemistry/*pharmacology

Aspartic Endopeptidases/*antagonists & inhibitors

Computer Simulation

Models; Biological

Models; Molecular

Plasmodium falciparum/enzymology

Protease Inhibitors/chemical synthesis/chemistry/*pharmacology

Quantitative Structure-Activity Relationship

Research Support; Non-U.S. Gov't

Publication and Content Type

ref (subject category)

art (subject category)