Total synthesis of balanol .2. Completion of the synthesis and investigation of the structure and reactivity of two key heterocyclic intermediates.

• A convergent enantioselective total synthesis of the natural product (-)-balanol (1) is described. In addition to benzophenone fragment 8, key intermediates are chiral bicyclic aziridine 3 and the corresponding epoxide 4, both of which undergo highly reg

Keyword

PROTEIN-KINASE-C; SEMIEMPIRICAL METHODS; CHIRAL AZIRIDINES; PARAMETERS; EPOXIDES; OPTIMIZATION; OXAZOLINES; INHIBITOR; ANALOGS; RING

Publication and Content Type

vet (subject category)

ovr (subject category)