Search: onr:"swepub:oai:DiVA.org:uu-90434" >
An automatic dose d...
An automatic dose dispenser for microtablets : A new concept for individual dosage of drugs in tablet form
-
- Bredenberg, Susanne (author)
- Uppsala universitet,Institutionen för farmaci
-
- Nyholm, Dag (author)
- Uppsala universitet,Neurologi
-
- Aquilonius, Sten-Magnus (author)
- Uppsala universitet,Neurologi
-
show more...
-
- Nyström, Christer (author)
- Uppsala universitet,Institutionen för farmaci
-
show less...
-
(creator_code:org_t)
- 2003
- 2003
- English.
-
In: International Journal of Pharmaceutics. - 0378-5173. ; 261:1-2, s. 137-146
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- A new concept for individualising the dosage of drugs in solid form is presented. The principle is based on the use of standardised units (microtablets), each containing a subtherapeutic amount of the active ingredient. The required dose is fine-tuned by counting out a specific number of these units. The microtablets are counted electronically from the attached cassette by the automatic dispensing device. The individual dose is set and the dispenser counts and delivers the correct number of microtablets. The usefulness of the automatic dispenser concept and acceptability of the apparatus were evaluated in patients with Parkinson’s disease (PD). After initial instruction on use of the dispenser, 20 patients operated it themselves. All patients were generally satisfied with their management of the automatic dispenser and most would be happy to use the device again. Further technical development is required before use in clinical practice, but the current prototype may be acceptable for some patients. It is concluded that the final version of the automatic dose dispenser concept will offer potential for improvement of drug administration for patients with PD or other diseases requiring individual dosage.
Keyword
- Individual dosage
- Drug dispensing device
- Parkinson’s disease
- Levodopa
- Microtablets
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database