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Long-term follow up of workers exposed to solvents

Edling, C. (author)
Ekberg, K. (author)
Ahlborg, Gunnar, 1948 (author)
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Alexandersson, R. (author)
Barregård, Lars, 1948 (author)
Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine
Ekenvall, L. (author)
Nilsson, L. (author)
Svensson, B. G. (author)
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 (creator_code:org_t)
1990
1990
English.
In: British journal of industrial medicine. - 0007-1072. ; 47:2, s. 75-82
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Long term occupational exposure to organic solvents may cause adverse effects to the central nervous system. This collaborative study between six Swedish departments of occupational medicine examines the overall prognosis in terms of working capacity, symptoms, and psychometric test performance for individuals occupationally exposed to organic solvents. After re-analyses of the data from an initial clinical investigation of 111 men, the subjects were divided into two subgroups: one group of 65 with symptoms but no impairment on the tests and one group of 46 with toxic encephalopathy (symptoms and test impairment). At least five years after the initial examination the subjects were asked to attend a re-examination that included a structured medical interview and a psychometric investigation. The results indicate that effects on the central nervous system persist even when exposure has ceased. In the group of 46 more men had stopped working and were receiving sickness or early retirement pensions. This group also had reduced activity levels with regard to everyday life, leisure activities, and education or training and more neuropsychiatric symptoms. There was no support for the view that a solvent induced toxic encephalopathy is a progressive disease comparable with presenile dementia such as Alzheimer's disease or Pick's disease. If a worker was removed from exposure when he presented symptoms without signs of impairment in intellectual function recovery was seen in most cases.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Keyword

Aged
Brain Diseases/*chemically induced
Humans
Leisure Activities
Male
Mental Disorders/*chemically induced
Middle Aged
Multicenter Studies as Topic
Occupational Diseases/*chemically induced
Prognosis
Psychological Tests
Psychometrics
Solvents/*adverse effects
Sweden
Time Factors

Publication and Content Type

ref (subject category)
art (subject category)

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