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HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment.
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- Edén, Arvid, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,University of Gothenburg
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- Fuchs, Dietmar (author)
- Medizinische Universität Innsbruck,Medical University of Innsbruck
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- Hagberg, Lars, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,University of Gothenburg
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- (creator_code:org_t)
- Oxford University Press (OUP), 2010
- 2010
- English.
- In: The Journal of infectious diseases. - : Oxford University Press (OUP). - 1537-6613 .- 0022-1899. ; 202:12, s. 1819-25
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Occasional cases of viral escape in cerebrospinal fluid (CSF) despite suppression of plasma human immunodeficiency virus type 1 (HIV-1) RNA have been reported. We investigated CSF viral escape in subjects treated with commonly used antiretroviral therapy regimens in relation to intrathecal immune activation and central nervous system penetration effectiveness (CPE) rank.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Anti-HIV Agents
- Blood-Brain Barrier
- Cerebrospinal Fluid
- virology
- Cross-Sectional Studies
- Enzyme-Linked Immunosorbent Assay
- Female
- HIV Infections
- drug therapy
- virology
- HIV-1
- isolation & purification
- Humans
- Male
- Middle Aged
- Neopterin
- analysis
- Plasma
- virology
- RNA
- Viral
- isolation & purification
- Reverse Transcriptase Polymerase Chain Reaction
- Treatment Outcome
- Viral Load
- virology
Publication and Content Type
- ref (subject category)
- art (subject category)
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- University of Gothenburg
- Chalmers University of Technology
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