Application of constant vs. variable relative biological effectiveness in treatment planning of intensity-modulated proton therapy.

• To investigate in a simulation study whether using a variable relative biological effectiveness (RBE) in calculation and optimization of intensity-modulated proton therapy (IMPT) instead of using an RBE of 1.1 would result in significant changes in the RBE-weighted dose (RWD) distributions.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Head and Neck Neoplasms

pathology

radiotherapy

Humans

Linear Energy Transfer

Organs at Risk

Protons

therapeutic use

Radiation Tolerance

Radiotherapy Planning

Computer-Assisted

methods

Radiotherapy

Intensity-Modulated

methods

Relative Biological Effectiveness

Publication and Content Type

ref (subject category)

art (subject category)