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Search: onr:"swepub:oai:gup.ub.gu.se/144674" > The effect of live,...

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  • Ahlgren, Cecilia,1946Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg (author)

The effect of live, attenuated measles vaccine and measles infection on measles antibody levels in serum and CSF of patients with multiple sclerosis or clinically isolated syndrome.

  • Article/chapterEnglish2011

Publisher, publication year, extent ...

  • Elsevier BV,2011

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/144674
  • https://gup.ub.gu.se/publication/144674URI
  • https://doi.org/10.1016/j.jneuroim.2011.04.002DOI
  • https://research.chalmers.se/publication/144674URI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • High occurrence of measles, rubella and varicella zoster antibodies has been used as a biomarker for MS (the MRZ test). We analyzed measles antibody titres with respect to measles infection/measles vaccination status in 166 patients with MS or clinically isolated syndrome. Fifty blood donors served as controls. Measles vaccination yielded CSF measles antibodies in fewer patients (62%) than measles infection did (87%, p=0.001) and yielded lower measles titres in both serum and CSF (p<0.001). Controls had lower CSF measles titres than patients with measles vaccination alone (p<0.001). Childhood vaccinations probably reduce the sensitivity of the MRZ diagnostic test for MS.

Subject headings and genre

  • Adolescent
  • Adult
  • Antibodies
  • Viral
  • blood
  • cerebrospinal fluid
  • Child
  • Preschool
  • Demyelinating Diseases
  • blood
  • cerebrospinal fluid
  • immunology
  • Female
  • Humans
  • Male
  • Measles
  • blood
  • cerebrospinal fluid
  • immunology
  • Measles Vaccine
  • immunology
  • therapeutic use
  • Middle Aged
  • Multiple Sclerosis
  • blood
  • cerebrospinal fluid
  • immunology
  • Vaccines
  • Attenuated
  • immunology
  • therapeutic use
  • Young Adult
  • Preschool

Added entries (persons, corporate bodies, meetings, titles ...)

  • Odén, Anders,1942Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper, matematisk statistik,Department of Mathematical Sciences, Mathematical Statistics,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)odena (author)
  • Haghighi, SaraGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg(Swepub:gu)xhagsa (author)
  • Andersen, Oluf,1941Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg(Swepub:gu)xandeo (author)
  • Bergström, Tomas,1950Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,University of Gothenburg(Swepub:gu)xberto (author)
  • Lycke, Jan,1956Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation,University of Gothenburg(Swepub:gu)xlycja (author)
  • Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering (creator_code:org_t)

Related titles

  • In:Journal of neuroimmunology: Elsevier BV235:1-2, s. 98-1031872-84210165-5728

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