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Incident lacunes influence cognitive decline: the LADIS study.

Jokinen, H (author)
Gouw, A A (author)
Madureira, S (author)
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Ylikoski, R (author)
Van Straaten, E C W (author)
van der Flier, W M (author)
Barkhof, F (author)
Scheltens, P (author)
Fazekas, F (author)
Schmidt, R (author)
Verdelho, A (author)
Ferro, J M (author)
Pantoni, L (author)
Inzitari, D (author)
Erkinjuntti, T (author)
Ladis Study Group, (author)
Wallin, Anders, 1950 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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 (creator_code:org_t)
2011
2011
English.
In: Neurology. - 0028-3878 .- 1526-632X. ; 76:22, s. 1872-8
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • In cerebral small vessel disease, the core MRI findings include white matter lesions (WML) and lacunar infarcts. While the clinical significance of WML is better understood, the contribution of lacunes to the rate of cognitive decline has not been established. This study investigated whether incident lacunes on MRI determine longitudinal cognitive change in elderly subjects with WML.

Keyword

Aged
Aged
80 and over
Brain
pathology
Brain Infarction
complications
pathology
Cognition Disorders
etiology
pathology
Female
Humans
Leukoaraiosis
pathology
Longitudinal Studies
Magnetic Resonance Imaging
Male
Neuropsychological Tests

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ref (subject category)
art (subject category)

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