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Simulating neurocognitive aging: effects of a dopaminergic antagonist on brain activity during working memory.
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- Fischer, Håkan (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institute
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- Nyberg, Lars (author)
- Umeå universitet,Diagnostisk radiologi,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för integrativ medicinsk biologi (IMB)
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- Karlsson, Sari (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institute
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- (creator_code:org_t)
- New York : Elsevier BV, 2010
- 2010
- English.
- In: Biological psychiatry. - New York : Elsevier BV. - 1873-2402 .- 0006-3223. ; 67:6, s. 575-80
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Previous correlational studies have indirectly linked dysfunctional dopaminergic neurotransmission to age-related cognitive deficits and associated reductions in task-induced functional brain activity.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Keyword
- Adult
- Aged
- Aging
- physiology
- Analysis of Variance
- Benzazepines
- pharmacology
- Brain
- blood supply
- drug effects
- radionuclide imaging
- Brain Mapping
- Dopamine Antagonists
- pharmacology
- Female
- Humans
- Image Processing
- Computer-Assisted
- methods
- Magnetic Resonance Imaging
- methods
- Male
- Memory
- Short-Term
- drug effects
- physiology
- Neuropsychological Tests
- Oxygen
- blood
- Positron-Emission Tomography
- methods
- Single-Blind Method
- Space Perception
- drug effects
- physiology
- Young Adult
- Aging
- Diagnostic radiology
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
- Fischer, Håkan
- Nyberg, Lars
- Karlsson, Sari
- Karlsson, P
- Brehmer, Yvonne
- Rieckmann, Anna
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- Macdonald, Stuar ...
- Farde, Lars
- Bäckman, Lars, 1 ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Surgery
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Radiology Nuclea ...
- Articles in the publication
- Biological psych ...
- By the university
- University of Gothenburg
- Stockholm University
- Umeå University
- Karolinska Institutet
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