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Rolofylline, an ade...
Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure.
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Massie, Barry M (author)
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O'Connor, Christopher M (author)
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Metra, Marco (author)
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Ponikowski, Piotr (author)
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Teerlink, John R (author)
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Cotter, Gad (author)
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Weatherley, Beth Davison (author)
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Cleland, John G F (author)
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Givertz, Michael M (author)
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Voors, Adriaan (author)
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DeLucca, Paul (author)
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Mansoor, George A (author)
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Salerno, Christina M (author)
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Bloomfield, Daniel M (author)
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Dittrich, Howard C (author)
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- Fu, Michael, 1963 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för akut och kardiovaskulär medicin,Institute of Medicine, Department of Emergeny and Cardiovascular Medicine
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(creator_code:org_t)
- 2010
- 2010
- English.
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In: The New England journal of medicine. - 1533-4406. ; 363:15, s. 1419-28
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https://doi.org/10.1...
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Abstract
Subject headings
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- Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved. We tested the hypothesis that the use of rolofylline, an adenosine A1-receptor antagonist, would improve dyspnea, reduce the risk of worsening renal function, and lead to a more favorable clinical course in patients with acute heart failure.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Keyword
- Acute Disease
- Adenosine A1 Receptor Antagonists
- Aged
- Diuretics
- adverse effects
- therapeutic use
- Double-Blind Method
- Female
- Heart Failure
- drug therapy
- mortality
- Humans
- Intention to Treat Analysis
- Kaplan-Meier Estimate
- Male
- Odds Ratio
- Patient Readmission
- Proportional Hazards Models
- Risk
- Treatment Failure
- Xanthines
- adverse effects
- therapeutic use
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Massie, Barry M
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O'Connor, Christ ...
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Metra, Marco
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Ponikowski, Piot ...
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Teerlink, John R
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Cotter, Gad
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show more...
-
Weatherley, Beth ...
-
Cleland, John G ...
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Givertz, Michael ...
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Voors, Adriaan
-
DeLucca, Paul
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Mansoor, George ...
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Salerno, Christi ...
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Bloomfield, Dani ...
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Dittrich, Howard ...
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Fu, Michael, 196 ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dermatology and ...
- Articles in the publication
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The New England ...
- By the university
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University of Gothenburg