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Charlson's weighted...
Charlson's weighted index of comorbidities is useful in assessing the risk of death in septic patients.
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Oltean, Simona (author)
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T Ţulescu, Doina (author)
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Bondor, Cosmina (author)
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Slavcovici, Adriana (author)
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Cismaru, Cristina (author)
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Lupşe, Mihaela (author)
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Muntean, Monica (author)
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Jianu, Cristian (author)
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Marcu, Cristian (author)
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- Oltean, Mihai, 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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(creator_code:org_t)
- Elsevier BV, 2012
- 2012
- English.
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In: Journal of critical care. - : Elsevier BV. - 0883-9441. ; 27:4, s. 370-375
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https://doi.org/10.1...
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Abstract
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- PURPOSE: We investigated the efficiency of the Charlson's weighted index of comorbidities (WIC) in predicting the risk of death in septic patients. MATERIALS AND METHODS: A single-center, 3-year analysis of all septic patients was conducted; WIC and organ failure assessed using the Sepsis-related Organ Failure Assessment (SOFA) score were calculated retrospectively. RESULTS: Of 250 septic patients, 60 patients (34%) had WIC above 2. Fifty-five patients (22%) died during the hospitalization. Increasing WIC was associated with increased mortality. Mean WIC differed significantly between survivors and nonsurvivors (P < .0001), and the univariate logistic regression revealed that risk of death depends significantly of WIC with odds ratio of 1.59 (95% confidence interval, 1.31-1.93; P < .001). The accuracy of prediction for the risk of death was 79.2%. Receiver operating characteristics curve indicated a WIC of 2 as a cutoff value, the association between WIC greater than 2, and the risk of death being described by an odds ratio of 1.87 (95% confidence interval, 1.017-3.457; P = .042); the area under the receiver operating characteristics curve in predicting mortality was 0.81 for the SOFA score and 0.68 for WIC; WIC correlated positively with SOFA (r = 0.27; P < .0001). CONCLUSION: In septic patients, WIC is predictive for hospital mortality, and the risk of death significantly depends on WIC.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Oltean, Simona
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T Ţulescu, Doina
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Bondor, Cosmina
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Slavcovici, Adri ...
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Cismaru, Cristin ...
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Lupşe, Mihaela
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show more...
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Muntean, Monica
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Jianu, Cristian
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Marcu, Cristian
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Oltean, Mihai, 1 ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
- Articles in the publication
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Journal of criti ...
- By the university
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University of Gothenburg