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- Zhou, Dapeng (author)
Immunologic mapping of glycomes: implications for cancer diagnosis and therapy.
- Article/chapterEnglish2011
Publisher, publication year, extent ...
- 2011
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/158481
- https://gup.ub.gu.se/publication/158481URI
Supplementary language notes
- Language:English
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- SwePubSwePub
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Notes
- Cancer associated glycoconjugates are important biomarkers, as exemplified by globo-H, CA125, CA15.3 and CA27.29. However, the exact chemical structures of many such biomarkers remain unknown because of technological limitations. In this article, we propose the "immunologic mapping" of cancer glycomes based on specific immune recognition of glycan structures, which can be hypothesized theoretically, produced chemically, and examined biologically by immuno-assays. Immunologic mapping of glycans not only provides a unique perspective on cancer glycomes, but also may lead to the invention of powerful reagents for diagnosis and therapy.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Andra medicinska och farmaceutiska grundvetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Other Basic Medicine hsv//eng
- Adaptive Immunity
- immunology
- Antigens
- Surface
- metabolism
- Epitopes
- immunology
- metabolism
- Galectins
- metabolism
- Glycoconjugates
- immunology
- metabolism
- Glycomics
- methods
- Humans
- Lectins
- metabolism
- Lectins
- C-Type
- metabolism
- Mass Spectrometry
- methods
- Neoplasms
- diagnosis
- drug therapy
- Polysaccharides
- metabolism
- Receptors
- Antigen
- T-Cell
- metabolism
- Signal Transduction
- immunology
Added entries (persons, corporate bodies, meetings, titles ...)
- Levery, Steven B (author)
- Hsu, Fong-Fu (author)
- Wang, Peng G (author)
- Almeida, Igor C (author)
- Li, Yunsen (author)
- Teneberg, Susann,1955Gothenburg University,Göteborgs universitet,Institutionen för biomedicin,Institute of Biomedicine(Swepub:gu)xtensu (author)
- Xu, Huaxi (author)
- Wang, Lai-Xi (author)
- Xia, Chengfeng (author)
- Ibrahim, Nuhad K (author)
- Michael, Katja (author)
- Göteborgs universitetInstitutionen för biomedicin (creator_code:org_t)
Related titles
- In:Frontiers in bioscience (Scholar edition)3, s. 1520-321945-0524
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