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Treatment of hepati...
Treatment of hepatitis C virus infection in adults and children: Updated Swedish consensus recommendations
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- Lagging, Martin, 1965 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,Dept Infect Dis, Inst Biomed, Univ Gothenburg, Gothenburg, Sweden
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- Duberg, Ann-Sofi, 1957- (author)
- Dept Infect Dis, Örebro Univ Hosp, Örebro, Sweden
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- Wejstål, Rune, 1952 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,Dept Infect Dis, Inst Biomed, Univ Gothenburg, Gothenburg, Sweden; Swedish Reference Grp Antiviral Therapy RAV, Karolinska Univ Hosp, Stockholm, Sweden
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- Weiland, O. (author)
- Karolinska Institutet
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- Lindh, Magnus, 1960 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine,Dept Infect Dis, Inst Biomed, Univ Gothenburg, Gothenburg, Sweden
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- Aleman, S. (author)
- Karolinska Institutet
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- Josephson, F. (author)
- Medical Products Agency (Läkemedelsverket), Uppsala, Sweden
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(creator_code:org_t)
- 2012-04-16
- 2012
- English.
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In: Scandinavian Journal of Infectious Diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 44:7, s. 502-521
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Abstract
Subject headings
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- Swedish recommendations for the treatment of hepatitis C virus (HCV) infection were updated at a recent expert meeting. Therapy for acute HCV infection should be initiated if spontaneous resolution does not occur within 12 weeks. The recommended standard-of-care therapy for chronic HCV genotype 1 infection is an HCV protease inhibitor in combination with peginterferon (peg-IFN) and ribavirin. Treatment is strongly recommended in patients with bridging fibrosis and cirrhosis, whereas in patients with less advanced fibrosis, deferring therapy may be preferential in light of likely therapeutic improvements in the near future. Patients with chronic genotype 2/3 infection should generally be treated with peg-IFN and ribavirin for 24 weeks. In patients with a very rapid viral response (i.e. HCV RNA below 1000 IU/ml on day 7), or favourable baseline characteristics and undetectable HCV RNA week 4, treatment can be shortened to 12 - 16 weeks, provided that no dose reductions are needed.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Keyword
- Hepatitis C virus
- guidelines
- HCV protease inhibitor
- interferon
- ribavirin
- sustained virological response
- human-immunodeficiency-virus
- weight-based ribavirin
- pegylated interferon-alpha
- liver fibrosis
- progression
- induced viral clearance
- genotype 1 infection
- 40kd plus
- ribavirin
- peginterferon alpha-2a
- coinfected patients
- Hepatitis C virus; guidelines; HCV protease inhibitor; interferon; ribavirin
- Infektionssjukdomar
Publication and Content Type
- ref (subject category)
- art (subject category)
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Lagging, Martin, ...
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Duberg, Ann-Sofi ...
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Wejstål, Rune, 1 ...
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Weiland, O.
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Lindh, Magnus, 1 ...
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Aleman, S.
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Josephson, F.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Other Medical an ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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- Articles in the publication
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Scandinavian Jou ...
- By the university
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University of Gothenburg
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Örebro University
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Karolinska Institutet