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- Lind, Marcus,1976Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine (author)
Incretin therapy and its effect on body weight in patients with diabetes
- Article/chapterEnglish2012
Publisher, publication year, extent ...
- Elsevier BV,2012
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/165347
- https://gup.ub.gu.se/publication/165347URI
- https://doi.org/10.1016/j.pcd.2012.04.006DOI
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- Language:English
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Notes
- Glucagon-like peptide 1 (GLP-1) analogues and dipeptidyl peptidase-4 (DPP-4) inhibitors are two classes of treatments for type 2 diabetes, which enhance the well-known 'incretin effect' of increased insulin secretion in response to food intake. This concise review introduces both types of incretin-based therapies and focuses on the extra-pancreatic effect of GLP-1 on body weight. As well as improving glycaemic control in subjects with type 2 diabetes, these treatments have the additional benefits of improving weight management in these patients, with GLP-1 receptor agonists causing weight loss and DPP-4 inhibitors being weight neutral. (C) 2012 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
- Glucagon-like peptide 1 (GLP-1)
- receptor agonist
- Dipeptidyl peptidase-4 (DPP-4) inhibitor
- Body
- glucagon-like peptide-1
- dipeptidyl peptidase-4 inhibitors
- life-style
- modification
- receptor agonists
- open-label
- exenatide
- mellitus
- glucose
- tolerability
- strategies
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- Göteborgs universitetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin (creator_code:org_t)
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- In:Primary Care Diabetes: Elsevier BV6:3, s. 187-1911751-9918
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