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Increased comorbidi...
Increased comorbidities in heart failure patients >/=85years but declined from >90years: Data from the Swedish Heart Failure Registry
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- Holmström, Alexandra (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska University Hospital, University of Gothenburg, Sweden.
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- Sigurjonsdottir, Runa (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska University Hospital, University of Gothenburg, Sweden.
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- Edner, M. (author)
- Karolinska Institutet
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- Jonsson, A. (author)
- Ryhov County Hospital, Jönköping, Sweden
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- Dahlström, Ulf (author)
- Östergötlands Läns Landsting,Linköpings universitet,Hälsouniversitetet,Avdelningen för kardiovaskulär medicin,Kardiologiska kliniken US
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- Fu, Michael, 1963 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Sahlgrenska University Hospital, University of Gothenburg, Sweden
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(creator_code:org_t)
- Elsevier BV, 2013
- 2013
- English.
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In: International journal of cardiology. - : Elsevier BV. - 1874-1754 .- 0167-5273. ; 167:6, s. 2747-2752
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Abstract
Subject headings
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- OBJECTIVES: Epidemiological studies of elderly heart failure (HF) patients (>/=85years) are limited with inconsistent findings. Our objective is to confirm and extend epidemiological study in elderly (>/=85years) patients using the Swedish Heart Failure Registry database. METHODS: This retrospective study included 8,347 HF patients aged /=85years. Elderly population was further divided into two subgroups: 11,412 patients were 85-90years and 4,477 patients were >90years. RESULTS: The >/=85year group was characterized by more women, higher systolic blood pressure (SBP), lower body-mass index (BMI), more than twice as many HF with normal left ventricular ejection fraction (HFNEF), higher incidence of cardiovascular and non-cardiovascular comorbidities and less use of proven therapeutics compared with the 90year subgroup had a decline in cardiovascular and non-cardiovascular comorbidities except renal insufficiency and anaemia which continued to increase with ageing (p<0.01). Tendency was the same regardless of gender but slightly different between systolic HF (SHF) and HFNEF. In the group with HFNEF, there were more women, higher SBP, lower N-terminal pro-B-type natriuretic peptide levels, less ischaemic heart disease, more hypertension and left bundle branch block regardless of age. Atrial fibrillation was more frequent in patients with HFNEF than with SHF in the elderly group (p<0.01). Patients with HFNEF in the >90year subgroup had increasing incidence of ischaemic heart disease compared to 85-90year group (p<0.01). CONCLUSIONS: HF patients >/=85years had increased cardiovascular and non-cardiovascular comorbidities but with a decline from >90years.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Keyword
- Heart failure
- Registry
- Epidemiology
- Elderly
- Comorbidity
Publication and Content Type
- ref (subject category)
- art (subject category)
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