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Lacrimal gland lesi...
Lacrimal gland lesions in Denmark between 1974 and 2007.
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von Holstein, Sarah Linéa (author)
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Therkildsen, Marianne Hamilton (author)
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Prause, Jan Ulrik (author)
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- Stenman, Göran, 1953 (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center
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Siersma, Volkert Dirk (author)
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Heegaard, Steffen (author)
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(creator_code:org_t)
- 2012-04-04
- 2013
- English.
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In: Acta ophthalmologica. - : Wiley. - 1755-3768 .- 1755-375X. ; 91:4, s. 349-354
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https://doi.org/10.1...
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Abstract
Subject headings
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- Purpose: To evaluate the incidence rate, distribution, patient characteristics and indications for surgical intervention of lacrimal gland lesions in Denmark between 1974 and 2007. Material and methods: All biopsied/surgically removed lacrimal gland lesions in Denmark during the period 1974-2007 were identified by searching two population-based registries. Specimens were collected and re-evaluated. The following data were collected: age, gender, indications for surgical intervention and local recurrence. Results: A total of 232 lesions from 210 patients with a histologically verified lesion of the lacrimal gland were included. The incidence rate of lacrimal gland lesions was 1.3/1000000/year. The overall annual age- and gender-adjusted incidence rate more than doubled during the study period, owing to an increase in non-malignant lesions. Approximately half of the lesions were neoplasms (119) and 55% (66) of these were malignant. Dacryops constituted 10% (24), inflammatory lesions 27% (62), normal tissue 12% (27), benign tumours 23% (53) and malignant tumours 29% (66). Patients with malignant neoplasms were significantly older than patients with benign neoplasms (63 versus 48years, p<0.001). The indication for surgical intervention was suspicion of a tumour in more than 90% of the neoplastic lesions and in 30% of the non-neoplastic lesions. Conclusion: Lacrimal gland lesions that require surgical evaluation are rare in the Danish population and represent a wide spectrum of diagnoses, mostly benign. The overall incidence rate of biopsied lacrimal gland lesions is increasing.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine (hsv//eng)
Keyword
- epithelial tumour
- incidence
- lacrimal gland
- lymphoid tumour
- non-neoplastic lesion
Publication and Content Type
- ref (subject category)
- art (subject category)
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