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  • Endale, Milkyas,1980Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology (author)

Anthraquinones of the roots of Pentas micrantha

  • Article/chapterEnglish2013

Publisher, publication year, extent ...

  • 2012-12-27
  • MDPI AG,2013
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/168714
  • https://gup.ub.gu.se/publication/168714URI
  • https://doi.org/10.3390/molecules18010311DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-356011URI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Pentas micrantha is used in the East African indigenous medicine to treat malaria. In the first investigation of this plant, the crude methanol root extract showed moderate antiplasmodial activity against the W2- (3.37 μg/mL) and D6-strains (4.00 μg/mL) of Plasmodium falciparum and low cytotoxicity (>450 μg/mL, MCF-7 cell line). Chromatographic separation of the extract yielded nine anthraquinones, of which 5,6-dihydroxylucidin-11-O-methyl ether is new. Isolation of a munjistin derivative from the genus Pentas is reported here for the first time. The isolated constituents were identified by NMR and mass spectrometric techniques and showed low antiplasmodial activities.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Ekberg, Annabel,1989Gothenburg University,Göteborgs universitet,Svenskt NMR-centrum vid Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Swedish NMR Centre at Göteborg University,Department of Chemistry and Molecular Biology (author)
  • Alao, John Patrick,1973Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology(Swepub:gu)xalajo (author)
  • Akala, Hoseah (author)
  • Ndakala, Albert (author)
  • Sunnerhagen, Per,1959Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology(Swepub:gu)xsuper (author)
  • Erdelyi, Mate,1975Gothenburg University,Göteborgs universitet,Svenskt NMR-centrum vid Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Swedish NMR Centre at Göteborg University,Department of Chemistry and Molecular Biology,organisk kemi(Swepub:uu)mateerde (author)
  • Yenesew, Abiy (author)
  • Göteborgs universitetInstitutionen för kemi och molekylärbiologi (creator_code:org_t)

Related titles

  • In:Molecules: MDPI AG18:1, s. 311-3211420-30491431-5157

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