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A standardized temp...
A standardized template for clinical studies in preterm birth.
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Myatt, Leslie (author)
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Eschenbach, David A (author)
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Lye, Stephen J (author)
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Mesiano, Sam (author)
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Murtha, Amy P (author)
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Williams, Scott M (author)
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Pennell, Craig E (author)
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- Jacobsson, Bo, 1960 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology
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- Sengpiel, Verena, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi,Institute of Clinical Sciences, Department of Obstetrics and Gynecology
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(creator_code:org_t)
- 2012-12-30
- 2012
- English.
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In: Reproductive sciences (Thousand Oaks, Calif.). - : Springer Science and Business Media LLC. - 1933-7205 .- 1933-7191. ; 19:5, s. 474-82
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Abstract
Subject headings
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- Preterm birth is a major societal and economic problem accounting for 80 to 90% of neonatal morbidity and mortality worldwide. It is recognized as a complex multifactorial condition comprising several distinct clinical phenotypes with different underlying etiologies. As animal models are expensive and fail to mimic the biology of spontaneous preterm birth in humans, understanding the pathophysiology requires detailed clinical studies. Meta-analyses and clinical translation of data, however, are limited by heterogeneity of study design and size, publication and reporting biases, definition of patient groups, and a lack of standard universal definitions. This article provides a harmonized open-source template for designing clinical studies addressing preterm birth.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Keyword
- Biomedical Research
- Female
- Gestational Age
- Glucocorticoids
- administration & dosage
- Humans
- Infant
- Newborn
- Infection
- complications
- Male
- Obesity
- complications
- Phenotype
- Pregnancy
- Pregnancy Complications
- Pregnancy
- Multiple
- Premature Birth
- etiology
- Research Design
- standards
- Sex Factors
- Stress
- Physiological
- Stress
- Psychological
- complications
- Uterine Cervical Diseases
- complications
- Uterine Diseases
- complications
- Uterine Hemorrhage
- complications
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Myatt, Leslie
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Eschenbach, Davi ...
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Lye, Stephen J
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Mesiano, Sam
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Murtha, Amy P
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Williams, Scott ...
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show more...
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Pennell, Craig E
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Jacobsson, Bo, 1 ...
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Sengpiel, Verena ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Obstetrics Gynae ...
- Articles in the publication
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Reproductive sci ...
- By the university
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University of Gothenburg