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Children and adoles...
Children and adolescents with follicular lymphoma have an excellent prognosis with either limited chemotherapy or with a "watch and wait" strategy after complete resection.
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Attarbaschi, Andishe (author)
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Beishuizen, Auke (author)
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Mann, Georg (author)
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Rosolen, Angelo (author)
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Mori, Tetsuya (author)
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Uyttebroeck, Anne (author)
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Niggli, Felix (author)
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Csoka, Monika (author)
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Krenova, Zdenka (author)
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- Mellgren, Karin, 1962 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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Kabickova, Edita (author)
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Chiang, Alan Ks (author)
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Reiter, Alfred (author)
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Williams, Denise (author)
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Burkhardt, Birgit (author)
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(creator_code:org_t)
- 2013-05-12
- 2013
- English.
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In: Annals of hematology. - : Springer Science and Business Media LLC. - 1432-0584 .- 0939-5555. ; 92:11, s. 1537-1541
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https://doi.org/10.1...
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Abstract
Subject headings
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- Data on clinical features and outcome in pediatric follicular lymphoma (pFL) are scarce. The aim of this retrospective study including 13 EICNHL and/or i-BFM study group members was to assess clinical characteristics and course in a series of 63 pFL patients. pFL was found to be associated with male gender (3:1), older age (72% ≥10years old), low serum LDH levels (<500U/l in 75%), grade 3 histology (in 88%), and limited disease (87% stage I/II disease), mostly involving the peripheral lymph nodes. Forty-four out of sixty-three patients received any polychemotherapy and 1/63 rituximab only, while 17/63 underwent a "watch and wait" strategy. Of 36 stage I patients, 30 had complete resections. Only one patient relapsed; 2-year event-free survival and overall survival were 94±5 and 100%, respectively, after a median follow-up of 2.2years. Conclusively, treatment outcome in pFL seems to be excellent with risk-adapted chemotherapy or after complete resection and an observational strategy only.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Follicular lymphoma
- Complete resection
- “Watch and wait”
- Outcome
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Attarbaschi, And ...
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Beishuizen, Auke
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Mann, Georg
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Rosolen, Angelo
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Mori, Tetsuya
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Uyttebroeck, Ann ...
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show more...
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Niggli, Felix
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Csoka, Monika
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Krenova, Zdenka
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Mellgren, Karin, ...
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Kabickova, Edita
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Chiang, Alan Ks
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Reiter, Alfred
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Williams, Denise
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Burkhardt, Birgi ...
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Pediatrics
- Articles in the publication
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Annals of hemato ...
- By the university
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University of Gothenburg