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Social disruption stress increases IL-6 levels and accelerates atherosclerosis in ApoE-/- mice.

Bernberg, Evelina, 1981 (author)
Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Wallenberg Laboratory,Institute of Medicine, Department of Molecular and Clinical Medicine
Ulleryd, Marcus A (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
Johansson, Maria E, 1977 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
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Bergström, Göran, 1964 (author)
Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Wallenberg Laboratory,Institute of Medicine, Department of Molecular and Clinical Medicine
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 (creator_code:org_t)
Elsevier BV, 2012
2012
English.
In: Atherosclerosis. - : Elsevier BV. - 0021-9150 .- 1879-1484. ; 221:2, s. 359-65
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • We have previously shown that different forms of stress have distinctive effects on atherogenesis in mice. We showed that social stress increase atherosclerosis in ApoE(-/-) mice, while more physical forms of stress do not. Here we evaluated the effect of social disruption (SDR) stress on atherogenesis and evaluated cytokine release after SDR-stress and five more physical stressors.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Fysiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Physiology (hsv//eng)

Keyword

Animals
Aortic Diseases
blood
etiology
genetics
metabolism
pathology
psychology
Apolipoproteins E
deficiency
genetics
Atherosclerosis
blood
etiology
genetics
metabolism
pathology
psychology
Chemokine CXCL1
blood
Corticosterone
blood
Disease Models
Animal
Disease Progression
Inflammation Mediators
blood
Interleukin-6
blood
Male
Mice
Mice
Inbred C57BL
Mice
Knockout
Risk Factors
Social Behavior
Stress
Psychological
complications
Time Factors
Up-Regulation

Publication and Content Type

ref (subject category)
art (subject category)

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Bernberg, Evelin ...
Ulleryd, Marcus ...
Johansson, Maria ...
Bergström, Göran ...
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MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Basic Medicine
and Physiology
Articles in the publication
Atherosclerosis
By the university
University of Gothenburg

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