Association between ambient temperature and acute myocardial infarction hospitalisations in Gothenburg, Sweden: 1985-2010

• Cardiovascular disease (CVD) is the number one cause of death globally and evidence is steadily increasing on the role of non-traditional risk factors such as meteorology and air pollution. Nevertheless, many research gaps remain, such as the association between these non-traditional risk factors and subtypes of CVD, such as acute myocardial infarction (AMI). The objective of this study was to investigate the association between daily ambient temperature and AMI hospitalisations using a case-crossover design in Gothenburg, Sweden (1985-2010). A secondary analysis was also performed for out-of-hospital ischemic heart disease (IHD) deaths. Susceptible groups by age and sex were explored. The entire year as well as the warm (April-September) and cold periods (October-March) were considered. In total 28,215 AMI hospitalisations (of 22,475 people) and 21,082 out-of-hospital IHD deaths occurred during the 26-year study period. A linear exposure-response corresponding to a 3% and 7% decrease in AMI hospitalisations was observed for an inter-quartile range (IQR) increase in the 2-day cumulative average of temperature during the entire year (11 degrees C) and the warm period (6 degrees C), respectively, with and without adjustment for PM(1)(0), NO(2), NOx or O(3). No heat waves occurred during the warm period. No evidence of an association in the cold period nor any association between temperature and IHD deaths in the entire year, warm or cold periods--with and without adjusting for PM(1)(0), NO(2), NOx or O(3) was found. No susceptible groups, based on age or sex, were identified either. The inverse association between temperature and AMI hospitalisations (entire year and warm period) in Gothenburg is in accordance with the majority of the few other studies that investigated this subtype of CVD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Adult

Age Factors

Air Pollutants

analysis

Air Pollution

Female

History

20th Century

History

21st Century

Hospital Mortality

Hospitalization

Humans

Male

Middle Aged

Myocardial Infarction

epidemiology

etiology

history

Patient Admission

Risk Factors

Seasons

Sex Factors

Sweden

epidemiology

Temperature

Young Adult

Publication and Content Type

ref (subject category)

art (subject category)