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Evaluation of the performance of novel Aβ isoforms as theragnostic markers in Alzheimer's disease: from the cell to the patient.
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- Portelius, Erik, 1977 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Gustavsson, Mikael K (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Zetterberg, Henrik, 1973 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- (creator_code:org_t)
- 2012-02-01
- 2012
- English.
- In: Neuro-degenerative diseases. - : S. Karger AG. - 1660-2862 .- 1660-2854. ; 10:1-4, s. 138-40
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Alzheimer's disease (AD) is the most common neurodegenerative disorder in the aging population and is characterized by extracellular plaques in the brain. The last decades have witnessed an explosion in studies of the role of amyloid-β (Aβ) metabolism and aggregation in the pathogenesis of AD which has been translated into novel promising therapies with putative disease-modifying effects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Keyword
- Alanine
- analogs & derivatives
- pharmacology
- Alzheimer Disease
- cerebrospinal fluid
- Amyloid Precursor Protein Secretases
- drug effects
- Amyloid beta-Peptides
- cerebrospinal fluid
- immunology
- Animals
- Antibodies
- Monoclonal
- metabolism
- Azepines
- pharmacology
- Dogs
- Enzyme Inhibitors
- pharmacology
- Humans
- Immunoprecipitation
- Mice
- Protein Isoforms
- cerebrospinal fluid
- Spectrometry
- Mass
- Matrix-Assisted Laser Desorption-Ionization
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Neuro-degenerative diseases (Search for host publication in LIBRIS)
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- University of Gothenburg
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