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Increased vitamin D...
Increased vitamin D-binding protein and decreased free 25(OH)D in obese women of reproductive age.
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- Karlsson, Therese, 1979 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
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Osmancevic, Amra, 1968 (author)
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- Jansson, Nina, 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
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- Hulthén, Lena, 1947 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
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- Holmäng, Agneta, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi,Institute of Neuroscience and Physiology, Department of Physiology
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Larsson, Ingrid, 1963 (author)
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(creator_code:org_t)
- 2013-04-21
- 2014
- English.
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In: European journal of nutrition. - : Springer Science and Business Media LLC. - 1436-6215 .- 1436-6207. ; 53:1, s. 259-267
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Abstract
Subject headings
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- PURPOSE: Obese subjects have lower circulating 25-hydroxyvitamin D (25(OH)D) than normal-weight subjects. Knowledge is scarce regarding differences in vitamin D-binding protein (DBP), free 25(OH)D, and intake of vitamin D between normal-weight and obese subjects. The purpose of this study was to examine intake and vitamin D status in obese compared with normal-weight women. METHODS: Between September 2009 and October 2011, 43 obese and 43 normal-weight women, 22-45years of age, mean BMI of 39.1±4.6 and 21.6±1.8kg/m(2), respectively, were recruited in the western Sweden region (latitude 57°N). Blood samples, data regarding diet, and sun exposure were collected. RESULTS: DBP concentrations were 320±121 and 266±104μg/mL (P=0.02) in obese and normal-weight women, respectively. Calculated free 25(OH)D was 13.3±5.5 (obese) and 23.7±10.7 (normal-weight) (P<0.001). The obese women had a 20.1nmol/L lower mean 25(HO)D concentration compared to normal-weight women (P<0.001). 56% of obese women and 12% of normal-weight women had 25(OH)D concentrations ≤50nmol/L. There was no statistically significant difference in total vitamin D intake between the groups. 39% of the women had a total vitamin D intake <7.5μg/day, the current national recommendation for vitamin D in Sweden. CONCLUSIONS: Obese women had higher DBP concentrations compared with normal-weight women and lower free 25(OH)D. The obese women were more likely to have 25(OH)D concentrations that could be considered suboptimal. Vitamin D intake was generally low in normal-weight and obese women of childbearing age.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Keyword
- Vitamin D
- Vitamin D intake
- Vitamin D status
- Vitamin D-binding protein
- Obesity
- 25(OH)D
Publication and Content Type
- ref (subject category)
- art (subject category)
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Karlsson, Theres ...
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Osmancevic, Amra ...
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Jansson, Nina, 1 ...
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Hulthén, Lena, 1 ...
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Holmäng, Agneta, ...
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Larsson, Ingrid, ...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Dermatology and ...
- Articles in the publication
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European journal ...
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University of Gothenburg