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- Danelius, EmmaGothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology (author)
Insight into β-Hairpin Stability: Interstrand Hydrogen Bonding
- Article/chapterEnglish2013
Publisher, publication year, extent ...
- 2013-08-28
- Georg Thieme Verlag KG,2013
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- LIBRIS-ID:oai:gup.ub.gu.se/185074
- https://gup.ub.gu.se/publication/185074URI
- https://doi.org/10.1055/s-0033-1339670DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-356023URI
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- Language:English
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Notes
- For evaluation of the role of interstrand hydrogen bonding for β-hairpin stability, two cyclic peptides differing only in side chain hydroxy-to-methyl substitution were designed and synthesized on solid phase following the Fmoc-t-Bu-Trt protection strategy. Subsequent to cyclization in solution, combined computational and experimental ensemble analysis revealed higher conformational stability of the peptide capable of interstrand hydrogen bonding.
Subject headings and genre
- NATURVETENSKAP Kemi hsv//swe
- NATURAL SCIENCES Chemical Sciences hsv//eng
- NATURVETENSKAP Kemi Organisk kemi hsv//swe
- NATURAL SCIENCES Chemical Sciences Organic Chemistry hsv//eng
- peptides - spectroscopy - macrocycles - β-hairpin - conformation
Added entries (persons, corporate bodies, meetings, titles ...)
- Brath, UlrikaGothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology(Swepub:gu)xbraul (author)
- Erdelyi, Mate,1975Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology,organisk kemi(Swepub:uu)mateerde (author)
- Göteborgs universitetInstitutionen för kemi och molekylärbiologi (creator_code:org_t)
Related titles
- In:Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry: Georg Thieme Verlag KG24:18, s. 2407-24100936-52141437-2096
- In:Synlett: Georg Thieme Verlag KG24:18, s. 2407-24101437-2096
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