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Vitamin B12 as a potential compliance marker for fish intake

Scheers, Nathalie, 1974 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Lindqvist, Helen, 1977 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,University of Gothenburg
Langkilde, Anna Maria, 1955 (author)
AstraZeneca AB
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Undeland, Ingrid, 1968 (author)
Chalmers tekniska högskola,Chalmers University of Technology
Sandberg, Ann-Sofie, 1951 (author)
Chalmers tekniska högskola,Chalmers University of Technology
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 (creator_code:org_t)
2013-11-30
2014
English.
In: European Journal of Nutrition. - : Springer Science and Business Media LLC. - 1436-6207 .- 1436-6215. ; 53:6, s. 1327-1333
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Objectives: The aim of the present study was to investigate whether the following four markers; Vitamin B12, selenium, vitamin D, and parvalbumin may be used as compliance markers for fish intake. Methods: Blood samples from a randomized cross-over herring intervention study (n=32) were analyzed by HPLC and immunochemistry. The criteria were that plasma or serum concentrations of candidate compliance markers after the herring diet should increase significantly compared to starting concentrations. In addition, the reference meat diet should not yield an increase in plasma concentration of the candidate marker. Results: Vitamin B12 and selenium met the set criteria for indicating a correlation between the marker and fish intake with significant increases in serum concentrations at 8.9% (p=0.008) and 4.6% (p=0.02) respectively after a 6-week herring intervention (5 meals a week). Parvalbumin and 25-hydroxy vitamin D3 levels did not increase significantly during the herring interventions. Conclusions: Vitamin B12 may be suitable as a compliance marker for fish intake. Although selenium also met the criteria, the change in selenium serum concentrations was small compared to the change in vitamin B12 levels.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)

Keyword

Biomarker
Marker
Compliance
Fish
Intake
Vitamin B12
Compliance

Publication and Content Type

ref (subject category)
art (subject category)

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