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Usefulness of Plasm...
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Aydin-Schmidt, BeritKarolinska Institutet
(author)
Usefulness of Plasmodium falciparum-specific rapid diagnostic tests for assessment of parasite clearance and detection of recurrent infections after artemisinin-based combination therapy.
- Article/chapterEnglish2013
Publisher, publication year, extent ...
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2013-10-01
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Springer Science and Business Media LLC,2013
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/190500
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https://gup.ub.gu.se/publication/190500URI
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https://doi.org/10.1186/1475-2875-12-349DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:127433589URI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Rapid diagnostic test (RDT) is an important tool for parasite-based malaria diagnosis. High specificity of RDTs to distinguish an active Plasmodium falciparum infection from residual antigens from a previous infection is crucial in endemic areas where residents are repeatedly exposed to malaria. The efficiency of two RDTs based on histidine-rich protein 2 (HRP2) and lactate dehydrogenase (LDH) antigens were studied and compared with two microscopy techniques (Giemsa and acridine orange-stained blood smears) and real-time polymerase chain reaction (PCR) for assessment of initial clearance and detection of recurrent P. falciparum infections after artemisinin-based combination therapy (ACT) in a moderately high endemic area of rural Tanzania.
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Mubi, MarycelinaKarolinska Institutet
(author)
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Morris, UlrikaKarolinska Institutet
(author)
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Petzold, Max,1973Gothenburg University,Göteborgs universitet,Akademistatistik,Centre for Applied Biostatistics(Swepub:gu)xpemax
(author)
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Ngasala, Billy E
(author)
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Premji, Zul
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Björkman, AndersKarolinska Institutet
(author)
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Mårtensson, AndreasKarolinska Institutet
(author)
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Karolinska InstitutetAkademistatistik
(creator_code:org_t)
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In:Malaria journal: Springer Science and Business Media LLC12:11475-2875
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